Title:
CRYSTAL FORM OF MULTI-SUBSTITUTED BENZENE RING COMPOUND MALEATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/078307
Kind Code:
A1
Abstract:
Provided are a crystal form of a multi-substituted benzene ring compound maleate, and a preparation method therefor and the use thereof. The crystal form of the multi-substituted benzene ring compound salt represented by formula II has good physicochemical stability, high solubility, less hygroscopicity, good flowability and more preparation process options, and is more suitable for industrial production, which is of great value for drug optimization and development.
Inventors:
WANG XUFAN (CN)
WENG QIUPING (CN)
WANG WENGUI (CN)
LI XIN (CN)
HU YONGHAN (CN)
WENG QIUPING (CN)
WANG WENGUI (CN)
LI XIN (CN)
HU YONGHAN (CN)
Application Number:
PCT/CN2021/123172
Publication Date:
April 21, 2022
Filing Date:
October 12, 2021
Export Citation:
Assignee:
SUZHOU SINOVENT PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D405/14; A61K31/4433; A61K31/4545; A61P35/00; A61P35/02; C07D401/14
Domestic Patent References:
| WO2020020374A1 | 2020-01-30 | |||
| WO2014049488A1 | 2014-04-03 | |||
| WO2013173441A2 | 2013-11-21 | |||
| WO2013075083A1 | 2013-05-23 | |||
| WO2020020374A1 | 2020-01-30 |
Foreign References:
| CN108314677A | 2018-07-24 | |||
| CN104080769A | 2014-10-01 | |||
| CN202011088764A | 2020-10-13 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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