Title:
CRYSTAL FORM OF OZANIMOD, AND PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/049632
Kind Code:
A1
Abstract:
The invention relates to a crystal form of ozanimod. Compared with known forms of ozanimod, the crystal form of ozanimod of the invention has one or more improved features. The invention also relates to a preparation method and a pharmaceutical composition of the crystal form of ozanimod. Also provided is a use of the crystal form for preparation of a medicament adapted for treatment of a disorder or a malcondition wherein modulation, activation, agonism, inhibition or antagonism of a selective sphingosine-1-phosphate receptor is medically indicated.
Inventors:
SHENG XIAOHONG (CN)
SHENG XIAOXIA (CN)
ZHENG JIANFENG (CN)
SHENG XIAOXIA (CN)
ZHENG JIANFENG (CN)
Application Number:
PCT/CN2016/099137
Publication Date:
March 22, 2018
Filing Date:
September 14, 2016
Export Citation:
Assignee:
SOLIPHARMA LLC (CN)
International Classes:
A61K31/4245; C07D271/06; A61P1/00; A61P11/00; A61P19/02; A61P25/28; A61P37/06
Foreign References:
CN102762100A | 2012-10-31 |
Other References:
JIANG, ZHI ET AL.: "non-official translation (Present Situation of Research and Development of the Receptors Modulator of SI P", PROGRESS IN PHARMACEUTICAL SCIENCES, vol. 40, no. 7, 31 July 2016 (2016-07-31), pages 548 - 554
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