Title:
CRYSTAL FORM OF SALT OF FUSED TRICYCLIC Γ-AMINO ACID DERIVATIVE AND PREPARATION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/011258
Kind Code:
A1
Abstract:
Provided are a crystal form of a salt of a fused tricyclic γ-amino acid derivative and the preparation and use thereof. As shown in formula (I), Y is selected from maleic acid, fumaric acid, haloid acid (preferably hydrobromic acid and hydrochloric acid), sulfuric acid, phosphoric acid, L-tartaric acid, citric acid, L-malic acid, hippuric acid, D-glucuronic acid, glycollic acid, mucic acid, succinic acid, lactic acid, orotic acid, pamoic acid, malonic acid, gentisic acid, oxalic acid, glutaric acid or saccharin.
Inventors:
LI YAO (CN)
SHI ZONGJUN (CN)
SHI SHAOHUI (CN)
LI SHENG (CN)
YAN PANGKE (CN)
ZHENG WEI (CN)
SHI ZONGJUN (CN)
SHI SHAOHUI (CN)
LI SHENG (CN)
YAN PANGKE (CN)
ZHENG WEI (CN)
Application Number:
PCT/CN2019/095857
Publication Date:
January 16, 2020
Filing Date:
July 12, 2019
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07C229/28; A61K31/195; A61P25/04; A61P25/06; A61P29/00
Domestic Patent References:
| WO2018050046A1 | 2018-03-22 |
Foreign References:
| CN1720219A | 2006-01-11 | |||
| CN101878193A | 2010-11-03 |
Other References:
YATES, P. ET AL.: "D ECOMPOSITON OF 1-DIAZO-3-(2, 2, 3-TRIMETHYLCYCLOPENT-3- ENYL) PROPAN-2-ONE.A NOVEL SYNTHESIS AND REARRANGEMENT OF A TRICYCLO[3.2.1.03, 6] OCTAN-4-ONE", TETRAHEDRON LETTERS, vol. 9, no. 20, 31 December 1968 (1968-12-31), pages 2493 - 2496, XP055483332
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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