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Title:
CRYSTAL FORMS OF OZANIMOD AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2018/033149
Kind Code:
A1
Abstract:
Provided are crystal forms of Ozanimod and a preparation method therefor. The provided crystal forms of Ozanimod comprise a crystal form CS9, a crystal form CS10, and a crystal form CS11 of Ozanimod, and can be used for treating autoimmune diseases, and specially multiple sclerosis and ulcerative colitis. The provided crystal forms of Ozanimod have advantages in at least one of the aspects: solubility, stability, hygroscopicity, processing performance and other aspects, provide a better new choice for preparing preparations containing Ozanimod, and are of great value for development of drugs.

Inventors:
CHEN MINHUA (CN)
ZHANG YANFENG (CN)
ZHAI XIAOTING (CN)
YAN KAIQIANG (CN)
YANG CHAOHUI (CN)
ZHANG XIAOYU (CN)
Application Number:
PCT/CN2017/098125
Publication Date:
February 22, 2018
Filing Date:
August 18, 2017
Export Citation:
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Assignee:
CRYSTAL PHARMACEUTICAL SUZHOU CO LTD (CN)
International Classes:
C07D271/06; A61K31/4245; A61P1/00; A61P1/04; A61P25/00; A61P37/02
Domestic Patent References:
WO2016164180A12016-10-13
WO2015066515A12015-05-07
Foreign References:
CN102762100A2012-10-31
CN102118972A2011-07-06
Other References:
See also references of EP 3502100A4
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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