Title:
CRYSTAL FORMS OF TETRA-HYDRO-N, N-DIMETHYL-2, 2-DIPHENYL-3-FURANMETHANAMINE HYDROCHLORIDE, PROCESSES FOR MAKING SUCH FORMS, AND THEIR PHARMACEUTICAL COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO/2017/013498
Kind Code:
A3
Abstract:
Polymorphic forms of tetrahydro-N,N-dimethyl-2,2-diphenyl-3- furanmethanamine hydrochloride (ANAVEX2-73) and a metabolite of tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73) are disclosed and characterized. Compositions and method for treatment of Alzheimer's disease that includes the polymorphic forms and metabolite of tetrahydro-N,N-dimethyl-2,2- diphenyl-3-furanmethanamine hydrochloride (ANAVEX2-73).
Inventors:
YORK PETER (GB)
LEONARD LUCY ANNE (GB)
LEDGER DANIEL MARK (GB)
DAINTREE LINDA SHARON (GB)
LEONARD LUCY ANNE (GB)
LEDGER DANIEL MARK (GB)
DAINTREE LINDA SHARON (GB)
Application Number:
PCT/IB2016/001181
Publication Date:
March 02, 2017
Filing Date:
July 19, 2016
Export Citation:
Assignee:
ANAVEX LIFE SCIENCES CORP (US)
International Classes:
C07D307/14; A61K31/341; A61P25/28
Domestic Patent References:
| WO1997030983A1 | 1997-08-28 | |||
| WO2010097641A1 | 2010-09-02 | |||
| WO2013008044A1 | 2013-01-17 |
Other References:
See also references of EP 3325456A4
Attorney, Agent or Firm:
SAUNDERS, Thomas, M. (US)
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