Title:
CRYSTALLINE POLYMORPHIC FORMS OF MONOSODIUM N-[8-(2-HYDROXYBENZOYL)AMINO]CAPRYLATE
Document Type and Number:
WIPO Patent Application WO2005107462
Kind Code:
A3
Abstract:
The present invention relates to crystalline polymorphic forms of monosodium N-[8-(2-hydroxybenzoyl)amino] caprylate ("SNAC"), including two hydrates, a methanol solvate, and an ethanol solvate, of SNAC. More specifically, the present invention provide six polymorphic forms of SNAC (hereafter referred to as Forms I-VI). The present invention also provides an amorphous form of SNAC.
Inventors:
LEVCHIK HALINA (US)
MAJURU SHINGAI (US)
SINGH BRAHMA (US)
HARRIS JAMILA (US)
MAJURU SHINGAI (US)
SINGH BRAHMA (US)
HARRIS JAMILA (US)
Application Number:
PCT/US2005/016126
Publication Date:
May 04, 2006
Filing Date:
May 06, 2005
Export Citation:
Assignee:
EMISPHERE TECH INC (US)
LEVCHIK HALINA (US)
MAJURU SHINGAI (US)
SINGH BRAHMA (US)
HARRIS JAMILA (US)
LEVCHIK HALINA (US)
MAJURU SHINGAI (US)
SINGH BRAHMA (US)
HARRIS JAMILA (US)
International Classes:
A61K31/609; A01N37/44; C07C235/46; C07C235/60
Foreign References:
| US20020065255A1 | 2002-05-30 |
Other References:
UNITED STATES PHARMACOLOGICAL CONVENTION INC.: "X-Ray Diffraction", vol. USP23-NF, 1995, UNITED STATES PHARMACOPEIA AND NATIONAL FORMULARY, ROCKVILLE US, pages: 1843 - 1844, XP001194829
BRITTAIN H.G.: "Polymorphism in pharmaceutical solids", 1999, MARCEL DEKKER, pages: 2 - 141-163, XP008062815
BRITTAIN H.G.: "Polymorphism in pharmaceutical solids", 1999, MARCEL DEKKER, pages: 2 - 141-163, XP008062815
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