Title:
CRYSTALS OF HYDROCHLORIDE OF PYRIDAZIN-3(2H)-ONE COMPOUND AND PROCESS FOR PRODUCTION OF SAME
Document Type and Number:
WIPO Patent Application WO/2010/074090
Kind Code:
A1
Abstract:
Provided are novel crystals of 4-bromo-6-(3-(4-chloro- phenyl)propoxy)-5-(pyridin-3-ylmethylamino)pyridazin-3(2H)-one monohydrochloride, and a process for production of same.
A-form crystals of 4-bromo-6-(3-(4-chlorophenyl)propoxy) -5-(pyridin-3-ylmethylamino)pyridazin-3(2H)-one monohydro- chloride represented by formula (1), which exhibit a powder X-ray diffraction pattern with characteristic peaks at diffraction angles (2θ) of 8.24, 11.24, 11.76, 16.48, 17.16, 17.80, 18.24, 19.80, 21.64, 22.56, 22.96, 23.68, 24.52, 25.92, 26.32, 27.12, 27.40, 28.00, 28.64, 29.28, 31.84, and 34.80°.
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Inventors:
KAWAHARA SHIRO (JP)
NISHITANI JUNICHI (JP)
NISHITANI JUNICHI (JP)
Application Number:
PCT/JP2009/071340
Publication Date:
July 01, 2010
Filing Date:
December 22, 2009
Export Citation:
Assignee:
NISSAN CHEMICAL IND LTD (JP)
KAWAHARA SHIRO (JP)
NISHITANI JUNICHI (JP)
KAWAHARA SHIRO (JP)
NISHITANI JUNICHI (JP)
International Classes:
C07D401/12; A61K31/501; A61P7/02
Domestic Patent References:
| WO1991016314A1 | 1991-10-31 | |||
| WO1991016314A1 | 1991-10-31 |
Foreign References:
| JP2008329799A | 2008-12-25 | |||
| JP2008330253A | 2008-12-25 |
Other References:
YOSHIHISA MATSUDA: "Takei Gensho o Shimesu Iyakuhin no Seizaika ni Okeru Sokudoronteki Anteisei Hyoka Ondo?Shitsudo Oyobi Hikari no Eikyo o Chushin to shite", PHARMACIA, vol. 43, no. 2, 2007, pages 111 - 116
NORISACHI TAKADA: "Soyaku Dankai ni Okeru Gen'yaku Form Screening to Sentaku", PHARM STAGE, vol. 6, no. 10, 2007, pages 20 - 25, XP008145548
MITSUHISA YAMANO: "Iyakuhin no Process Kenkyu ni Okeru Kessho Takei Gensho eno Torikumi", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, vol. 65, no. 9, 2007, JAPAN, pages 907(69) - 913(75)
TAKEHISA HATA: "ANDAs (Kan'yaku Shin'yaku Shinsei):Iyakuhin no Kessho Takei", PHARM STAGE, vol. 8, no. 6, 15 September 2008 (2008-09-15), pages 62 - 69
"Iyakuhin no Zanryu Yobai Guideline ni Tsuite", IYAKUSHIN, no. 307, 1998
See also references of EP 2374805A4
PHARMACIA, vol. 45, no. 4, 2009, pages 327
NORISACHI TAKADA: "Soyaku Dankai ni Okeru Gen'yaku Form Screening to Sentaku", PHARM STAGE, vol. 6, no. 10, 2007, pages 20 - 25, XP008145548
MITSUHISA YAMANO: "Iyakuhin no Process Kenkyu ni Okeru Kessho Takei Gensho eno Torikumi", JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY, vol. 65, no. 9, 2007, JAPAN, pages 907(69) - 913(75)
TAKEHISA HATA: "ANDAs (Kan'yaku Shin'yaku Shinsei):Iyakuhin no Kessho Takei", PHARM STAGE, vol. 8, no. 6, 15 September 2008 (2008-09-15), pages 62 - 69
"Iyakuhin no Zanryu Yobai Guideline ni Tsuite", IYAKUSHIN, no. 307, 1998
See also references of EP 2374805A4
PHARMACIA, vol. 45, no. 4, 2009, pages 327
Attorney, Agent or Firm:
SENMYO, Kenji et al. (JP)
Spring name Kenji (JP)
Spring name Kenji (JP)
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