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Title:
CT IMAGE-BASED METHOD AND DEVICE FOR REALIZING LUNG NODULE ADAPTIVE MATCHING BY BONE REGISTRATION
Document Type and Number:
WIPO Patent Application WO/2021/109988
Kind Code:
A1
Abstract:
A CT image-based method for realizing lung nodule adaptive matching by bone registration, comprising the following steps: data preparation, extraction of lung and bone point cloud data, three-dimensional point cloud data registration, and lung nodule adaptive matching. In said method, firstly, three-dimensional point cloud rigid transformation registration is performed on lung image data and lung nodule data on the basis of the characteristic of small changes in human bone, so as to achieve the alignment of the lung and the lung nodule data before and after follow-up; secondly, an FGR algorithm is used, and in terms of operation speed and registration accuracy, the FGR algorithm is obviously superior to local refinement algorithms such as ICP; thirdly, the RMSE is used as a lung point cloud registration error, achieving lung nodule adaptive matching, so that the lung nodule registration requires less manual intervention, has a high degree of automation, and achieves an accurate registration result; and fourthly, normalization processing is performed on CT image data, so that the robustness of the algorithm can be improved. The method can be widely applied to CT devices of different models and DICOM data of different pixel spacing values.

Inventors:
CAI FEIYUE (CN)
LAI YAOMING (CN)
LUO ZHAOYANG (CN)
QIAN DONGDONG (CN)
QIN JITAO (CN)
WEI JUN (CN)
Application Number:
PCT/CN2020/133091
Publication Date:
June 10, 2021
Filing Date:
December 01, 2020
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Assignee:
PERCEPTION VISION MEDICAL TECH CO LTD (CN)
PERCEPTION VISION DATA TECH CO LTD (CN)
International Classes:
G06T7/33
Domestic Patent References:
WO2006057724A22006-06-01
Foreign References:
CN111127527A2020-05-08
CN109009435A2018-12-18
CN109816655A2019-05-28
Other References:
HONG, H. ; LEE, J. ; YIM, Y.: "Automatic lung nodule matching on sequential CT images", COMPUTERS IN BIOLOGY AND MEDICINE, NEW YORK, NY, US, vol. 38, no. 5, 1 May 2008 (2008-05-01), US, pages 623 - 634, XP022683881, ISSN: 0010-4825, DOI: 10.1016/j.compbiomed.2008.02.010
ZHANG CHUNSHENG: "Non-Rigid Registration of Lung Surfaces Based on CT Images", CHINESE DOCTORAL DISSERTATIONS FULL-TEXT DATABASE (ELECTRONIC JOURNAL), 1 July 2012 (2012-07-01), XP055818954
Attorney, Agent or Firm:
GENUINEWAYS INC. (CN)
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