Title:
CULTURE MEDIUM FOR ASSISTED REPRODUCTION TECHNOLOGY
Document Type and Number:
WIPO Patent Application WO/2019/240255
Kind Code:
A1
Abstract:
Provided are: an assisted reproductive technology method characterized by the use of a culture medium containing albumin having a low caprylic acid content; a culture medium for said method; and an agent for use in said culture medium.
Inventors:
YAO TATSUMA (JP)
ASAYAMA YUTA (JP)
SUGIYAMA YUI (JP)
ASAYAMA YUTA (JP)
SUGIYAMA YUI (JP)
Application Number:
PCT/JP2019/023628
Publication Date:
December 19, 2019
Filing Date:
June 14, 2019
Export Citation:
Assignee:
FUSO PHARMACEUTICAL IND (JP)
International Classes:
C12N5/071; C07K14/76
Domestic Patent References:
| WO2014192938A1 | 2014-12-04 |
Foreign References:
| JP2014520535A | 2014-08-25 | |||
| JPH04352727A | 1992-12-07 | |||
| JP2006506435A | 2006-02-23 | |||
| JP2015506673A | 2015-03-05 | |||
| JP2015509381A | 2015-03-30 |
Other References:
HAYASHI, SHIGEHIRO ET AL.: "Octanoic Acid Density in In-Vitro Fertilization Culture Solutions and Effects on Embryogenesis", JOURNAL OF JAPAN SOCIETY FOR REPRODUCTIVE MEDICINE, vol. 61, no. 4, pages 340
SCHEIDER, W. ET AL.: "An effective method for defatting albumin using resin columns", BIOCHIM. BIOPHYS. ACTA, vol. 221, 1970, pages 376 - 378, XP025931472, DOI: 10.1016/0005-2795(70)90280-1
QUINN, P. ET AL.: "Effect of fatty acids on fertilization and development of mouse embryos in vitro", J. ANDROL., vol. 3, 1982, pages 440 - 444, XP055663104
FREDRICKSON, J. ET AL.: "The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model", J. ASSIST. REPROD. GENET., vol. 32, 2015, pages 1517 - 1524, XP035572588, DOI: 10.1007/s10815-015-0560-9
LEONARD, P. H. ET AL.: "Variability in protein quality used for embryo culture: embryotoxicity of the stabilizer octanoic acid", FERTIL. STERN., vol. 100, no. 2, 2013, pages 544 - 549, XP028685698, DOI: 10.1016/j.fertnstert.2013.03.034
BIOCHIM. BIOPHYS. ACTA, vol. 1702, no. 1, 2004, pages 9 - 17
See also references of EP 3808837A4
SCHEIDER, W. ET AL.: "An effective method for defatting albumin using resin columns", BIOCHIM. BIOPHYS. ACTA, vol. 221, 1970, pages 376 - 378, XP025931472, DOI: 10.1016/0005-2795(70)90280-1
QUINN, P. ET AL.: "Effect of fatty acids on fertilization and development of mouse embryos in vitro", J. ANDROL., vol. 3, 1982, pages 440 - 444, XP055663104
FREDRICKSON, J. ET AL.: "The impact of the protein stabilizer octanoic acid on embryonic development and fetal growth in a murine model", J. ASSIST. REPROD. GENET., vol. 32, 2015, pages 1517 - 1524, XP035572588, DOI: 10.1007/s10815-015-0560-9
LEONARD, P. H. ET AL.: "Variability in protein quality used for embryo culture: embryotoxicity of the stabilizer octanoic acid", FERTIL. STERN., vol. 100, no. 2, 2013, pages 544 - 549, XP028685698, DOI: 10.1016/j.fertnstert.2013.03.034
BIOCHIM. BIOPHYS. ACTA, vol. 1702, no. 1, 2004, pages 9 - 17
See also references of EP 3808837A4
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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