CULTURE MEDIUM FOR MESENCHYMAL STEM CELLS

WIPO Patent Application WO/2016/027850

A1

The present invention addresses the problem of providing a means for achieving the previously difficult long-term growth and cultivation of mesenchymal stem cells, without using a special device, equipment/materials, etc. The abovementioned problem is solved by the provision of a culture medium for mesenchymal stem cells that has a reduced amount of the seven non-essential amino acids, glycine, alanine, serine, proline, asparagine, aspartic acid, and glutamic acid.

WO/1993/014634	PROTECTIVE EFFECTS OF MUTATED SUPERANTIGENS
WO/2001/070022	COATING MATERIALS FOR BIOLOGICAL TISSUES, COATED BIOLOGICAL TISSUES AND METHOD OF COATING BIOLOGICAL TISSUES
JP2816971	INDUSTRIAL APPLICABILITY [Title of Invention] Recombinant hepatic parenchymal cell growth factor

JIN YONGHUI (JP)
HARATA IKUE (JP)
SENDA SHO (JP)
OZAWA HIROKI (JP)
KOBAYASHI TSUYOSHI (JP)
TOGUCHIDA JUNYA (JP)
IKEYA MAKOTO (JP)

PCT/JP2015/073349

February 25, 2016

August 20, 2015

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AJINOMOTO KK (JP)
UNIV KYOTO (JP)

C12N5/00; A61K35/55; A61K35/56; A61P19/00; A61P19/02; A61P19/04; A61P43/00; C12N5/0775

WO2013081436A1	2013-06-06
WO2013032052A1	2013-03-07

JP2006325445A	2006-12-07
EP2083071A1	2009-07-29
JP2013530721A	2013-08-01

CHOI, KYUNG-MIN ET AL.: "Effect of essential and nonessential amino acid compositions on the in vitro behavior of human mesenchymal stem cells", KOREAN JOURNAL OF CHEMICAL ENGINEERING, vol. 24, no. 6, 2007, pages 1058 - 1063, XP009500244
HIGUERA, GUSTAVO A. ET AL.: "Patterns of Amino Acid Metabolism by Proliferating Human Mesenchymal Stem Cells", TISSUE ENGINEERING. PART A, vol. 18, no. 5-6, 2012, pages 654 - 664, XP055407451
See also references of EP 3184627A4

TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)

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