Title:
CULTURE METHOD FOR STABLE UNDIFFERENTIATED PROLIFERATION OF PLURIPOTENT STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2014/119219
Kind Code:
A1
Abstract:
Provided are a culture method for the undifferentiated proliferation of pluripotent stem cells, said method comprising a step for culturing the pluripotent stem cells in a culture medium that is characterized by containing at least one member selected from the group consisting of ethanolamine, ethanolamine analogs and pharmaceutically acceptable salts thereof and the concentration of β-mercaptoethanol in the culture medium being substantially 0 or not greater than 9 μM, etc.
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Inventors:
SENDA SHO (JP)
YOSHIDA TOMOMI (JP)
OKAMOTO SATORU (JP)
KURIYAMA YOKO (JP)
KITAZAWA MANABU (JP)
HARADA IKUE (JP)
SUGIMOTO NAO (JP)
YOSHIDA TOMOMI (JP)
OKAMOTO SATORU (JP)
KURIYAMA YOKO (JP)
KITAZAWA MANABU (JP)
HARADA IKUE (JP)
SUGIMOTO NAO (JP)
Application Number:
PCT/JP2013/085263
Publication Date:
August 07, 2014
Filing Date:
December 27, 2013
Export Citation:
Assignee:
AJINOMOTO KK (JP)
International Classes:
C12N5/0735; C12N1/00; C12N5/10; C12N15/09
Domestic Patent References:
| WO2012104936A1 | 2012-08-09 | |||
| WO2011043405A1 | 2011-04-14 | |||
| WO2012019122A2 | 2012-02-09 | |||
| WO2005063968A1 | 2005-07-14 | |||
| WO1992013526A1 | 1992-08-20 |
Foreign References:
| JP2011505152A | 2011-02-24 | |||
| JP2011078370A | 2011-04-21 | |||
| JP2006325445A | 2006-12-07 | |||
| JP2009542247A | 2009-12-03 | |||
| US8569061B2 | 2013-10-29 |
Other References:
ES SAIBO: "iPS Saibo no Baiyo ni StemSure? Series", WAKO JUN'YAKU JIHO, vol. 78, no. 4, 2010, pages 20, XP008180667
"StemSureR Series", WAKO BIOWINDOW, no. 120, 2012, pages 16, XP055274552
CELL, vol. 126, 2006, pages 663 - 76
NATURE COMMUNICATIONS, vol. 3, 2012, pages 1236
NATURE METHODS, vol. 8, 2011, pages 424 - 429
NATURE, vol. 385, 1997, pages 810
SCIENCE, vol. 280, 1998, pages 1256
NATURE BIOTECHNOLOGY, vol. 17, 1999, pages 456
NATURE, vol. 394, 1998, pages 369
NATURE GENETICS, vol. 22, 1999, pages 127
PROC. NATL. ACAD. SCI. USA, vol. 96, 1999, pages 14984
NATURE GENETICS, vol. 24, 2000, pages 109
GREEN ET AL.: "Protective Groups in Organic Synthesis, 3rd Edition,", 1999, JOHN WILEY SONS, INC
See also references of EP 2952579A4
"StemSureR Series", WAKO BIOWINDOW, no. 120, 2012, pages 16, XP055274552
CELL, vol. 126, 2006, pages 663 - 76
NATURE COMMUNICATIONS, vol. 3, 2012, pages 1236
NATURE METHODS, vol. 8, 2011, pages 424 - 429
NATURE, vol. 385, 1997, pages 810
SCIENCE, vol. 280, 1998, pages 1256
NATURE BIOTECHNOLOGY, vol. 17, 1999, pages 456
NATURE, vol. 394, 1998, pages 369
NATURE GENETICS, vol. 22, 1999, pages 127
PROC. NATL. ACAD. SCI. USA, vol. 96, 1999, pages 14984
NATURE GENETICS, vol. 24, 2000, pages 109
GREEN ET AL.: "Protective Groups in Organic Synthesis, 3rd Edition,", 1999, JOHN WILEY SONS, INC
See also references of EP 2952579A4
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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