Title:
CURCUMIN ANALOGUES FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO2001040188
Kind Code:
A9
Abstract:
The present invention is directed to curcumin analogs (I), wherein Y is OH, halogen, or CF3; Z is H, OH, OR1, halogen, or CF3; X1 and X2 are independently C or N; and A is as defined in the application; exhibiting anti-tumor and anti-angiogenic properties, pharmaceutical formulations including such compounds and methods of using such compounds.
Inventors:
SNYDER JAMES P (US)
DAVIS MATTHEW C (US)
ADAMS BRIAN (US)
SHOJI MAMORU (US)
LIOTTA DENNIS C (US)
FERSTL EVA M (US)
SUNAY USTUN B (US)
DAVIS MATTHEW C (US)
ADAMS BRIAN (US)
SHOJI MAMORU (US)
LIOTTA DENNIS C (US)
FERSTL EVA M (US)
SUNAY USTUN B (US)
Application Number:
PCT/US2000/032870
Publication Date:
July 25, 2002
Filing Date:
December 04, 2000
Export Citation:
Assignee:
UNIV EMORY (US)
SNYDER JAMES P (US)
DAVIS MATTHEW C (US)
ADAMS BRIAN (US)
SHOJI MAMORU (US)
LIOTTA DENNIS C (US)
FERSTL EVA M (US)
SUNAY USTUN B (US)
SNYDER JAMES P (US)
DAVIS MATTHEW C (US)
ADAMS BRIAN (US)
SHOJI MAMORU (US)
LIOTTA DENNIS C (US)
FERSTL EVA M (US)
SUNAY USTUN B (US)
International Classes:
A61K31/065; A61K31/10; A61K31/121; A61K31/122; A61K31/15; A61K31/351; A61K31/352; C07D317/54; A61K31/36; A61K31/404; A61K31/4439; A61K31/45; A61K31/4545; A61K31/46; A61P35/00; A61P43/00; C07C33/28; C07C33/48; C07C43/23; C07C45/29; C07C45/62; C07C45/74; C07C49/233; C07C49/235; C07C49/248; C07C49/255; C07C49/697; C07C49/747; C07C49/753; C07C225/22; C07C235/34; C07C251/40; C07C275/24; C07C317/10; C07C317/18; C07C321/20; C07D209/34; C07D213/63; C07D213/68; C07D295/205; C07D309/20; C07D309/22; C07D309/38; C07D311/58; C07D317/50; C07D401/06; C07D401/14; C07D451/02; C07D451/06; (IPC1-7): C07D213/63; A61P35/00; C07C49/235; C07C49/248; C07C317/10; C07C33/48; C07D451/02
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