Title:
CYANOGUANIDINES AND CYANOAMIDINES AS ERBB2 AND EGFR INHIBITORS
Document Type and Number:
WIPO Patent Application WO2004046101
Kind Code:
A3
Abstract:
Cyanoguanidine quinazoline and cyanoamidine quinazolamine derivatives that are useful in the treatment of hyperproliferative diseases are disclosed. Use of the compounds of the invention to manufacture therapeutic compositions for the treatment of hyperproliferative diseases in mammals is also disclosed.
Inventors:
WALLACE ELI
TOPALOV GEORGE
ZHAO QIAN
TOPALOV GEORGE
ZHAO QIAN
Application Number:
PCT/US2003/035670
Publication Date:
September 16, 2004
Filing Date:
November 10, 2003
Export Citation:
Assignee:
ARRAY BIOPHARMA INC (US)
International Classes:
A61P31/18; A61P35/00; C07D239/94; C07D401/12; C07D403/12; C07D405/04; C07D417/14; (IPC1-7): C07D239/94; A61K31/4706; A61K31/517; A61P31/18; A61P35/00; C07D215/42
Foreign References:
| US6184225B1 | 2001-02-06 |
Other References:
See also references of EP 1567506A4
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