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Title:
CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR
Document Type and Number:
WIPO Patent Application WO/2006/137509
Kind Code:
A1
Abstract:
It is intended to provide a pharmaceutical composition which is excellent as an agent for preventing or treating a disease related to an immunological action such as an autoimmune disease. The pharmaceutical composition comprises one or more members selected from the group consisting of PPAR regulators and one or more members selected from the group consisting of aminoalcohol derivatives having the following general formula (I): (I) (wherein R1 and R2, which are the same or different, represent a hydrogen atom or the like, R3 represents a C1-C6 alkyl group or a hydroxymethyl group, R4 represents a hydrogen atom, a C1-C6 alkyl group or the like, R5 represents a phenyl group substituted with 1 to 3 groups selected from the group consisting of a hydrogen atom, a halogen atom, a cyano group, a C1-C6 alkyl group and the like, X represents a vinylene group (CH=CH group), an oxygen atom or the like, Y represents a single bond, an oxygen atom or the like, Z represents a single bond, a C1-C8 alkylene group or the like and n represents an integer of 2 or 3) and pharmacologically acceptable salts thereof.

Inventors:
NISHI TAKAHIDE
SHIMOZATO TAKAICHI
KAGARI TAKASHI
DOI HIROMI
Application Number:
PCT/JP2006/312568
Publication Date:
December 28, 2006
Filing Date:
June 23, 2006
Export Citation:
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Assignee:
SANKYO CO (JP)
NISHI TAKAHIDE
SHIMOZATO TAKAICHI
KAGARI TAKASHI
DOI HIROMI
International Classes:
A61K31/40; A61K31/137; A61K31/421; A61K31/426; A61K31/427; A61K31/4439; A61K31/517; A61K45/00; A61P1/04; A61P17/06; A61P19/02; A61P25/00; A61P37/02; A61P37/06; C07D207/335
Domestic Patent References:
WO1997045141A11997-12-04
WO2003059880A12003-07-24
WO1994008943A11994-04-28
WO1996006068A11996-02-29
Foreign References:
JPH1180026A1999-03-23
Other References:
See also references of EP 1915994A4
Attorney, Agent or Firm:
Yaguchi, Toshiaki c/o DAIICHI SANKYO COMPANY (LIMITED 1-16-13, Kitakasa, Edogawa-ku Tokyo 30, JP)
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