CYCLIC AMINES AS BROMODOMAIN INHIBITORS

Title:

CYCLIC AMINES AS BROMODOMAIN INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2014/080290

Kind Code:

A3

Abstract:

The present disclosure relates to compounds of formula I, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.

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Inventors:

FAIRFAX DAVID JOHN (US)
DUFFY BRYAN CORDELL (US)
MARTIN GREGORY SCOTT (US)
QUINN JOHN FREDERICK (US)
LIU SHUANG (US)
WAGNER GREGORY STEVEN (US)
YOUNG PETER RONALD (US)

Application Number:

PCT/IB2013/003122

Publication Date:

October 23, 2014

Filing Date:

November 20, 2013

Export Citation:

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Assignee:

RVX THERAPEUTICS INC (CA)

International Classes:

C07D401/04; A61K31/517; A61P3/10; A61P9/00; A61P25/00; A61P35/00; A61P37/06; C07D239/91

Domestic Patent References:

WO2005075432A1

2005-08-18

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