CYCLIC AMINO ALCOHOL COMPOUND

WIPO Patent Application WO/2010/087244

A1

A novel low-molecular compound having an immunosuppressive action. The compound is a compound having general formula (I) or a pharmacologically acceptable salt thereof. [In the formula, the substituents are defined as shown below: R1 and R2 each represents a hydrogen atom or the like.; R3 represents a hydrogen atom or the like.; Y represents an ethylene group or the like; Z represents a single bond or the like; R5 represents a hydrogen atom or the like; and R6 and R7 each represents a hydrogen atom or the like.]

JP3569428	PRODUCTION OF HOMOALLYLAMINES
JP2001508811	[Title of the Invention] Anthranilic acid derivative as a cGMP-phosphodiesterase inhibitor

NAKAMURA TSUYOSHI
MIZUNO YUMIKO
SEKIGUCHI YUKIKO
SHIMOZATO TAKAICHI

PCT/JP2010/050534

August 05, 2010

January 19, 2010

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DAIICHI SANKYO CO LTD (JP)
NAKAMURA TSUYOSHI
MIZUNO YUMIKO
SEKIGUCHI YUKIKO
SHIMOZATO TAKAICHI

C07D333/20; A61K31/381; A61P1/04; A61P1/16; A61P3/10; A61P7/06; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P21/00; A61P21/04; A61P25/00; A61P25/14; A61P29/00; A61P31/04; A61P37/02; A61P37/06; A61P37/08; C07D333/22

WO2006137509A1	2006-12-28
WO1994008943A1	1994-04-28

JP2003267974A	2003-09-25
JP2008530135A	2008-08-07

RAN ZHU ET AL.: "Asymmetric Synthesis of Conformationally Constrained Fingolimod Analogues-Discovery of an Orally Active Sphingosine 1-Phosphate Receptor Type-1 Agonist and Receptor Type-3 Antagonist", JOURNAL OF MEDICINAL CHEMISTRY, vol. 50, no. 25, 2007, pages 6428 - 6435, XP008108140, DOI: doi:10.1021/jm7010172

ISHIBASHI Koki et al. (JP)
Kimiki Ishibashi (JP)

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