Title:
CYCLIC PEPTIDE AND PREPARATION METHOD THEREFOR, AND COMPLEX COMPRISING SAME AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/046469
Kind Code:
A1
Abstract:
Provided is a cyclic peptide, which has a sequence of cyclo(X1X2X3X4X5X6), wherein X1 is asparagine; X2 is glycine or sarcosine; X3 is arginine; X4 is selected from a group consisting of threonine, tyrosine, and phenylalanine; X5 is lysine; and X6 is selected from a group consisting of tyrosine, valine, and glutamic acid. Provided is a preparation method for the cyclic peptide. Provided is a complex, comprising the cyclic peptide, a linker, and a chelating agent. Provided is a use of the complex as a radionuclide-labeled targeting molecule. Provided is a radionuclide labeling method, comprising bringing a complex that chelates a radionuclide into contact with an object to be labeled by the radionuclide.
More Like This:
Inventors:
SHAN CHANGYU (CN)
ZENG DEXING (CN)
CHEN YINFEI (CN)
LI WENJIE (CN)
ZENG DEXING (CN)
CHEN YINFEI (CN)
LI WENJIE (CN)
Application Number:
PCT/CN2023/116515
Publication Date:
March 07, 2024
Filing Date:
September 01, 2023
Export Citation:
Assignee:
HEXIN SUZHOU PHARMACEUTICAL TECH CO LTD (CN)
International Classes:
C07K7/64; A61K51/08; A61P35/00; C07K1/13; C07K7/06
Domestic Patent References:
| WO2012045719A2 | 2012-04-12 |
Foreign References:
| CN112079900A | 2020-12-15 | |||
| CN103483422A | 2014-01-01 | |||
| CN103948947A | 2014-07-30 | |||
| CN104984371A | 2015-10-21 | |||
| CN114773433A | 2022-07-22 | |||
| US20150045302A1 | 2015-02-12 |
Attorney, Agent or Firm:
BEIJING WANHUIDA LAW FIRM (CN)
Download PDF: