Title:
CYCLOALKYL-DIONE DERIVATIVES AND METHODS OF THEIR USE
Document Type and Number:
WIPO Patent Application WO/2014/165633
Kind Code:
A8
Abstract:
The present invention is directed to compounds of formula I: wherein A is n is 0, 1, or 2; m is 0 or 1; R1 is H or C1-6alkyl and R2 is H, C1-6alkyl, C1-6alkaryl, aryl, or heteroaryl; and X is O or NH. Tautomers, enantiomers, and diastereomers, as well as pharmaceutically acceptable salt forms, of compounds of formula I are also within the scope of the invention. Methods of preparing and using the compounds of formula I are also described.
Inventors:
BALLATORE CARLO (US)
BRUNDEN KURT R (US)
LEE VIRGINIA M Y (US)
SMITH AMOS B III (US)
TROJANOWSKI JOHN Q (US)
WANG XIAOZHAO (US)
BRUNDEN KURT R (US)
LEE VIRGINIA M Y (US)
SMITH AMOS B III (US)
TROJANOWSKI JOHN Q (US)
WANG XIAOZHAO (US)
Application Number:
PCT/US2014/032742
Publication Date:
December 11, 2014
Filing Date:
April 03, 2014
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
International Classes:
C07C49/597
Attorney, Agent or Firm:
CALDWELL, John, W. et al. (Cira Centre 12th Floor,2929 Arch Stree, Philadelphia PA, US)
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