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Patent Searching and Data


Title:
CYCLOBUTYL-FUSED PYRROLIDINE DERIVATIVES, THEIR PREPARATION METHODS AND THEIR MEDICAL USE
Document Type and Number:
WIPO Patent Application WO/2008/148279
Kind Code:
A1
Abstract:
A novel cyclobutyl-fused pyrrolidine derivatives of formula (I) in which the substituents are defined in the description, their preparation methods, their compositions and their use as therapeutical agent, particularly as dipeptidyl peptidase IV (DPPIV) inhibitor.

Inventors:
TANG PENGCHO (CN)
LIN ZHIGANG (CN)
YANG JIALIANG (CN)
ZHAO FUQIANG (CN)
WANG YANG (CN)
WANG QIAN (CN)
Application Number:
PCT/CN2007/070927
Publication Date:
December 11, 2008
Filing Date:
October 19, 2007
Export Citation:
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Assignee:
SHANGHAI HENGRUI PHARM CO LTD (CN)
TANG PENGCHO (CN)
LIN ZHIGANG (CN)
YANG JIALIANG (CN)
ZHAO FUQIANG (CN)
WANG YANG (CN)
WANG QIAN (CN)
International Classes:
C07D209/52; A61K31/403; A61P3/10
Foreign References:
CN1427826A2003-07-02
CN1703399A2005-11-30
Other References:
AMBROSIO J.C.L. ET AL.: "Reductive decarboxylation of bicyclic prolinic systems. A new approach to the enantioselective synthesis of the Geissman-Waiss lactone, X-ray structure determination of a key lactone intermediate", JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, vol. 14, no. 1, 2003, pages 28 - 29, 32 - 33
Attorney, Agent or Firm:
JEEKAI & PARTNERS (Jinyu TowerA129 West Xuan Wu Men Street, XiCheng District, Beijing 1, CN)
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