Title:
CYCLOPENTYL ADENOSINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/241699
Kind Code:
A1
Abstract:
The present disclosure relates to a cyclopentyl adenosine derivative and a pharmaceutical use thereof. Specifically, the present disclosure provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R1-R8 are as defined in the description.
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Inventors:
XIONG LIZE (CN)
ZHU LINGJIAN (CN)
LI WANRONG (CN)
JI CHANGJIN (CN)
HUANG JIAN (CN)
ZHU LINGJIAN (CN)
LI WANRONG (CN)
JI CHANGJIN (CN)
HUANG JIAN (CN)
Application Number:
PCT/CN2023/100742
Publication Date:
December 21, 2023
Filing Date:
June 16, 2023
Export Citation:
Assignee:
SHANGHAI SENHUI MEDICINE CO LTD (CN)
SHANGHAI FOURTH PEOPLES HOSPITAL (CN)
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI FOURTH PEOPLES HOSPITAL (CN)
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
International Classes:
C07H19/167; A61K31/7076; A61P29/00
Foreign References:
| CN112004541A | 2020-11-27 | |||
| CN110022881A | 2019-07-16 | |||
| US20070087994A1 | 2007-04-19 | |||
| US20060276428A1 | 2006-12-07 |
Other References:
ILIA KORBOUKH, HULL-RYDE EMILY A., RITTINER JOSEPH E., RANDHAWA AMARJIT S., COLEMAN JENNIFER, FITZPATRICK BRENDAN J., SETOLA VINCE: "Orally Active Adenosine A 1 Receptor Agonists with Antinociceptive Effects in Mice", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 55, no. 14, 26 July 2012 (2012-07-26), US , pages 6467 - 6477, XP055383481, ISSN: 0022-2623, DOI: 10.1021/jm3004834
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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