Title:
CYCLOPROPANAMIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2023/054626
Kind Code:
A1
Abstract:
Provided is a cyclopropanamide derivative. A compound represented by formula (1) [wherein: n represents an integer of 0, 1, 2 or 3; ring A represents (1) 4-pyridyl which may be substituted with 1 to 4 substituents, or (2) phenyl which is substituted with 2 to 5 substituents; and ring B represents (1) a C3-20 alicyclic group which may be substituted with 1 to 6 substituents, or (2) a 4- to 20-membered non-nitrogen-containing non-aryl heterocyclic group which may be substituted with 1 to 6 substituents] or a pharmaceutically acceptable salt thereof. The present invention pertains to a cyclopropanamide derivative having an effect of suppressing nerve hyperexcitability, a pharmaceutically acceptable salt thereof and a medicinal composition containing the same as an active ingredient.
Inventors:
AIHARA YOSHINORI (JP)
FURUTA TOMOYUKI (JP)
FURUTA TOMOYUKI (JP)
Application Number:
PCT/JP2022/036547
Publication Date:
April 06, 2023
Filing Date:
September 29, 2022
Export Citation:
Assignee:
SUMITOMO PHARMA CO LTD (JP)
International Classes:
A61K45/00; A61K31/165; A61K31/335; A61K31/337; A61K31/343; A61K31/44; A61P21/00; A61P25/00; A61P25/08; C07C233/59; C07C233/60; C07C233/62; C07D213/64; C07D305/14; C07D307/93; C07D309/08; C07D407/12; C07D493/08
Domestic Patent References:
| WO2020163268A1 | 2020-08-13 | |||
| WO2019189781A1 | 2019-10-03 |
Foreign References:
| JP2020502213A | 2020-01-23 | |||
| JP2008535801A | 2008-09-04 | |||
| JP2008533154A | 2008-08-21 |
Attorney, Agent or Firm:
YAMAMOTO, Shusaku et al. (JP)
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