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Title:
CYCLOPROPANAMINE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2014/058071
Kind Code:
A1
Abstract:
The present invention provides a compound that: has a lysine-specific demethylase-1-inhibiting effect; and provides utility as a drug for preventing or treating schizophrenia, Alzheimer's disease, Parkinson's disease, and Huntington chorea. The present invention pertains to a compound expressed by formula (1) or salt thereof (where (A) represents a hydrocarbon group optionally having a substitution group or a heterocyclic group optionally having a substitution group; (B) represents a benzene ring optionally having a substitution group; (R1), (R2), and (R3) independently represent a hydrogen, a hydrocarbon group optionally having a substitution group, or a heterocyclic ring group optionally having a substitution group; (A) and (R1) can be bonded together to form, with an adjacent nitrogen atom, a cyclic group optionally having a substitution group; and (R2) and (R3) can be bonded together to form, with an adjacent hydrogen atom, a cyclic group optionally having a substitution group).

Inventors:
TOMITA NAOKI (JP)
TOMITA DAISUKE (JP)
TOMINARI YUSUKE (JP)
IMAMURA SHINICHI (JP)
MORIMOTO SHINJI (JP)
KOJIMA TAKUTO (JP)
TOYOFUKU MASASHI (JP)
HATTORI YASUSHI (JP)
KAKU TOMOHIRO (JP)
ITO MITSUHIRO (JP)
Application Number:
PCT/JP2013/077863
Publication Date:
April 17, 2014
Filing Date:
October 11, 2013
Export Citation:
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Assignee:
TAKEDA PHARMACEUTICAL (JP)
International Classes:
A61K31/166; C07C237/40; A61K31/167; A61K31/415; A61K31/4453; A61P25/14; A61P25/16; A61P25/28; A61P43/00; C07C237/30; C07C237/38; C07D231/40; C07D295/18; C12N9/99; C12N15/09
Domestic Patent References:
WO2010143582A12010-12-16
WO2010084160A12010-07-29
WO2010043721A12010-04-22
WO2011035941A12011-03-31
WO2011042217A12011-04-14
WO2012135113A22012-10-04
WO2012013728A12012-02-02
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WO2012156531A22012-11-22
WO2012156537A22012-11-22
WO2013022047A12013-02-14
WO2013057320A12013-04-25
WO2010084160A12010-07-29
WO2010043721A12010-04-22
WO2011035941A12011-03-31
WO2011042217A12011-04-14
WO2010143582A12010-12-16
WO2012156531A22012-11-22
WO2012156537A22012-11-22
WO2012135113A22012-10-04
Foreign References:
JP2012036124A2012-02-23
US20100324147A12010-12-23
Other References:
BECKER ET AL., NATURE, vol. 442, 2006, pages 31 - 32
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Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
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