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Title:
THE CYSTEINE-RICH REGION OF RESPIRATORY SYNCYTIAL VIRUS AND METHODS OF USE THEREFOR
Document Type and Number:
WIPO Patent Application WO2006023029
Kind Code:
A3
Abstract:
The invention features methods and compositions featuring an RSV Glycoprotein fragment for modulating an immune response in a subject.

Inventors:
POLACK FERNANDO PEDRO (US)
IRUSTA PABLO MARTIN (US)
KLEEBERGER STEVEN R (US)
Application Number:
PCT/US2005/021538
Publication Date:
May 04, 2006
Filing Date:
June 16, 2005
Export Citation:
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Assignee:
UNIV JOHNS HOPKINS (US)
POLACK FERNANDO PEDRO (US)
IRUSTA PABLO MARTIN (US)
KLEEBERGER STEVEN R (US)
International Classes:
A61K38/00; C07K2/00; C12Q1/70
Other References:
BRIDEAU RJ ET AL: "Protection of cotton rats against human respiratory syncytial virus by vaccination with a novel chimeric FG glycoprotein.", JOURNAL OF GENERAL VIROLOGY., vol. 70, October 1989 (1989-10-01), pages 2637 - 2644, XP008062373
TAYLOR G ET AL: "Resistance to bovine respiratory syncytial virus (BRSV) induced in calves by a recombinant bovine herpesvirus-1 expressing the attachment glycoprotein of BRSV.", J GEN VIROL., vol. 79, no. 7, July 1998 (1998-07-01), pages 1759 - 1767, XP002996180
MONICK MM ET AL: "Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin.", J BIOL CHEM., vol. 278, no. 52, December 2003 (2003-12-01), pages 53035 - 53044, XP002996181
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