Title:
CYTOKINE FUSION PROTEINS
Document Type and Number:
WIPO Patent Application WO/2019/147837
Kind Code:
A3
Abstract:
Provided are cytokine fusion proteins comprising a first cytokine fused to a second cytokine, for example, interleukin-2 (IL-2) or interferon-β (IFN-β) fused to the N-terminus of tumor necrosis factor-α (TNF-α), and related compositions and methods of use thereof for treating cancers, either as standalone agents or in combination with autologous tumor vaccines and/or immune checkpoint modulatory agents.
Inventors:
CHEN YIYOU (US)
GUO DAGANG (CN)
GUO DAGANG (CN)
Application Number:
PCT/US2019/014985
Publication Date:
October 31, 2019
Filing Date:
January 24, 2019
Export Citation:
Assignee:
BEIJING PERCANS ONCOLOGY CO LTD (CN)
International Classes:
C07K14/55; A61P35/00; C07K14/525; C07K19/00
Domestic Patent References:
| WO2016180715A1 | 2016-11-17 |
Foreign References:
| US20050069521A1 | 2005-03-31 | |||
| US20010010925A1 | 2001-08-02 |
Attorney, Agent or Firm:
ROGEL, Mark E. et al. (US)
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