CYTOKINE MODULATORS AND RELATED METHOD OF USE

WIPO Patent Application WO2005025586

B1

A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and/or inflammatory response, and subsequently treat, diseases and/or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.

RANDOLPH RUSSELL K (US)
ROH-SCHMIDT HAERI (US)

PCT/IB2004/051742

May 06, 2005

September 10, 2004

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ACCESS BUSINESS GROUP INT LLC (US)
RANDOLPH RUSSELL K (US)
ROH-SCHMIDT HAERI (US)

A61K31/05; A61K31/122; A61K36/07; A61K36/185; A61K36/28; A61K36/30; A61K36/324; A61K36/45; A61K36/53; A61K36/61; A61K36/63; A61K36/738; A61K36/74; A61K36/82; A61K36/87; A61K36/906; A61P37/00; (IPC1-7): A61K35/78; A61P37/00; A61K31/05; A61K31/122

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