Title:
CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS
Document Type and Number:
WIPO Patent Application WO2003009807
Kind Code:
A3
Abstract:
Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituded phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infraction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.
Inventors:
WANG BING
ZHANG YONG-KANG
CHEN JIAN
ZHANG WEI
SONG JIANGAO
DEL BALZO UGHETTA
BROWN LESLEY
MILLER GUY
ZHANG YONG-KANG
CHEN JIAN
ZHANG WEI
SONG JIANGAO
DEL BALZO UGHETTA
BROWN LESLEY
MILLER GUY
Application Number:
PCT/US2002/023509
Publication Date:
April 29, 2004
Filing Date:
July 23, 2002
Export Citation:
Assignee:
GALILEO LAB INC (US)
International Classes:
A61K8/00; A61K8/30; C07D295/18; A61K31/05; A61K31/055; A61K31/06; A61K31/085; A61K31/09; A61K31/10; A61K31/122; A61K31/15; A61K31/166; A61K31/18; A61K31/192; A61K31/21; A61K31/235; A61K31/277; A61K31/28; A61K31/30; A61K31/315; A61K31/343; A61K31/353; A61K31/36; A61K31/381; A61K31/4164; A61K31/4184; A61K31/426; A61K31/4425; A61K31/444; A61K31/4453; A61K31/5375; A61K31/555; A61K31/662; A61K31/7024; A61K33/32; A61P1/04; A61P3/10; A61P5/24; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P17/00; A61P17/02; A61P17/06; A61P17/10; A61P17/16; A61P19/02; A61P21/00; A61P25/00; A61P25/02; A61P25/16; A61P25/18; A61P25/28; A61P27/02; A61P29/00; A61P37/06; A61P43/00; A61Q19/00; A61Q19/02; C07C39/21; C07C39/373; C07C39/44; C07C43/215; C07C43/23; C07C45/30; C07C45/71; C07C49/737; C07C49/747; C07C50/34; C07C69/007; C07C69/76; C07C69/94; C07C205/17; C07C205/20; C07C205/22; C07C205/35; C07C205/57; C07C235/42; C07C255/15; C07C255/36; C07C255/53; C07C255/54; C07C311/29; C07C317/22; C07D213/30; C07D213/53; C07D231/22; C07D231/26; C07D233/24; C07D233/64; C07D235/08; C07D277/20; C07D277/24; C07D277/30; C07D277/34; C07D295/22; C07D295/26; C07D307/83; C07D311/72; C07D317/62; C07D333/16; C07F1/08; C07F9/40; C07H13/08; (IPC1-7): A61K31/185; A61K31/075
Other References:
DATABASE CAPLUS [online] SATO ET AL.: "Tyrosinase inhibitors containing desverastroles and cosmetics containing them", XP002974280, accession no. STN Database accession no. 1998:176285
DATABASE CAPLUS [online] SAKAI ET AL.: "Skin-lightening cosmetics containing chlorophorin as tyrosine inhibitor", XP002974281, accession no. STN Database accession no. 1998:62544
DATABASE CAPLUS [online] COTIAS ET AL.: "Longistyline C, antibiotic isolated from lonchocarpus longistyllus. Preliminary results of its pharmacological properties", XP002974282, accession no. STN Database accession no. 1980:437284
DATABASE CAPLUS [online] CHRISTENSEN ET AL.: "Excelsaoctaphenol, a stilbene dimer from clorophora excelsa", XP002974283, accession no. STN Database accession no. 1989:454148
DATABASE CAPLUS [online] MARTA ET AL.: "Synthesis of longistylin A, B, C, D and other new prenylated stilbenes", XP002974284, accession no. STN Database accession no. 1980:110611
DATABASE CAPLUS [online] SAKAI ET AL.: "Skin-lightening cosmetics containing chlorophorin as tyrosine inhibitor", XP002974281, accession no. STN Database accession no. 1998:62544
DATABASE CAPLUS [online] COTIAS ET AL.: "Longistyline C, antibiotic isolated from lonchocarpus longistyllus. Preliminary results of its pharmacological properties", XP002974282, accession no. STN Database accession no. 1980:437284
DATABASE CAPLUS [online] CHRISTENSEN ET AL.: "Excelsaoctaphenol, a stilbene dimer from clorophora excelsa", XP002974283, accession no. STN Database accession no. 1989:454148
DATABASE CAPLUS [online] MARTA ET AL.: "Synthesis of longistylin A, B, C, D and other new prenylated stilbenes", XP002974284, accession no. STN Database accession no. 1980:110611
Download PDF: