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Patent Searching and Data


Title:
CYTOTOXIN COMPOUND AND METHOD OF ISOLATION
Document Type and Number:
WIPO Patent Application WO2005079471
Kind Code:
A3
Abstract:
A compound or groups of compounds, present in an active principle, derived from tunicates of the species Synoicum adareanum, as well as to pharmaceutical compositions comprising these compounds. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.

Inventors:
BAKER BILL J (US)
DIYABALANAGE THUSHARA (US)
MCCLINTOCK JAMES B (US)
AMSLER CHARLES D (US)
Application Number:
US2005005098W
Publication Date:
October 13, 2005
Filing Date:
February 17, 2005
Export Citation:
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Assignee:
UNIV SOUTH FLORIDA (US)
UAB RESEARCH FOUNDATION (US)
BAKER BILL J (US)
DIYABALANAGE THUSHARA (US)
MCCLINTOCK JAMES B (US)
AMSLER CHARLES D (US)
International Classes:
A61K31/335; A61K31/365; A61K35/56; C07D315/00; (IPC1-7): C07D315/00; A61K31/335
Foreign References:
US6750247B22004-06-15
Other References:
See also references of EP 1718631A4
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