Title:
D TYPE AMINO ACID DEHYDROGENASE
Document Type and Number:
WIPO Patent Application WO/2019/031574
Kind Code:
A1
Abstract:
An enzyme having features (a) and (b). (a) Has D-amino acid reversible dehydrogenating activity. (b) Is a hexamer of a polypeptide having an amino acid sequence that identifies at least 80% with a SEQ ID No. 2 amino acid sequence.
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Inventors:
AKITA HIRONAGA (JP)
NAKAMICHI YUUSUKE (JP)
WATANABE MASAHIRO (JP)
MATSUSHIKA AKINORI (JP)
MORITA TOMOTAKE (JP)
NAKAMICHI YUUSUKE (JP)
WATANABE MASAHIRO (JP)
MATSUSHIKA AKINORI (JP)
MORITA TOMOTAKE (JP)
Application Number:
PCT/JP2018/029889
Publication Date:
February 14, 2019
Filing Date:
August 09, 2018
Export Citation:
Assignee:
AIST (JP)
International Classes:
C12N15/09; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/06; C12N15/31; C12N15/53; C12P13/04
Foreign References:
| JP2017108740A | 2017-06-22 |
Other References:
DATABASE nucleotide [O] 2 December 2016 (2016-12-02), "Thermosyntropha lipolytica DSM 11003 genome assembly, contig:EK14DRAFT_scaffold00009.9, whole genome shotgun sequence.", XP055571789, Database accession no. FQWY01000010
AKITA, HIRONAGA ET AL.: "Thermostable artificial NADP+- dependent D-amino acid dehydrogenase: its creation and application", BITAMIN = VITAMINS, vol. 90, no. 11, 2016, pages 544 - 554, XP009518803, ISSN: 0006-386X
AKITA, H. ET AL.: "Creation of a thermostable NADP+-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain Al meso- diaminopimelate dehydrogenase by site-directed mutagenesis", BIOTECHNOL LETT, vol. 34, 2012, pages 1693 - 1699, XP035105215
See also references of EP 3666894A4
AKITA, HIRONAGA ET AL.: "Thermostable artificial NADP+- dependent D-amino acid dehydrogenase: its creation and application", BITAMIN = VITAMINS, vol. 90, no. 11, 2016, pages 544 - 554, XP009518803, ISSN: 0006-386X
AKITA, H. ET AL.: "Creation of a thermostable NADP+-dependent D-amino acid dehydrogenase from Ureibacillus thermosphaericus strain Al meso- diaminopimelate dehydrogenase by site-directed mutagenesis", BIOTECHNOL LETT, vol. 34, 2012, pages 1693 - 1699, XP035105215
See also references of EP 3666894A4
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
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