Title:
DATA ACQUISITION METHOD IN A MASS SPECTROMETER
Document Type and Number:
WIPO Patent Application WO/2019/102798
Kind Code:
A1
Abstract:
The present invention provides a data acquisition method in a mass spectrometer, which comprises: a. providing an ion source to generate precursor ions; b. feeding the precursor ions into a first mass analyzer, wherein the first mass analyzer selects at least one mass window such that the precursor ions located outside the mass window pass through the first mass analyzer and the precursor ions located within the mass window cannot pass through the first mass analyzer; c. feeding the precursor ions passing through the first mass analyzer into a collision cell for collisional dissociation, to generate product ions; d. feeding the product ions into a second mass analyzer for mass analysis and recording a spectrum; and e. repeating Steps b to d, wherein each time when Step b is repeatedly performed, the selected mass window does not overlap with all the mass windows previously selected; and after all the mass windows in a mass range have been selected, the repetition is stopped. The present invention can effectively improve the ion utilization efficiency of the data-independent acquisition method and reduce the difficulty in data post-processing.
Inventors:
ZHANG XIAOQIANG (CN)
HUANG YUNQING (CN)
SUN WENJIAN (CN)
HUANG YUNQING (CN)
SUN WENJIAN (CN)
Application Number:
PCT/JP2018/040129
Publication Date:
May 31, 2019
Filing Date:
October 29, 2018
Export Citation:
Assignee:
SHIMADZU CORP (JP)
International Classes:
H01J49/00
Foreign References:
| US20150279640A1 | 2015-10-01 | |||
| US6717130B2 | 2004-04-06 | |||
| US8809770B2 | 2014-08-19 | |||
| US5672870A | 1997-09-30 |
Attorney, Agent or Firm:
KYOTO INTERNATIONAL PATENT LAW OFFICE (JP)
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