Title:
DECELLULARIZED TISSUE
Document Type and Number:
WIPO Patent Application WO/2016/136633
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a decellularized tissue having excellent cell adhesion properties. Provided is a decellularized tissue prepared by decellularizing a biological tissue, said decellularized tissue being characterized in that the ratio of endothermic energy amount, in terms of dry mass, of the decellularized tissue to the biological tissue before the decellularization is 0.70 or greater when measured by differential scanning calorimetry. The ratio by mass of DNA amount, in terms of dry mass, of the decellularized tissue to the biological tissue before the decellularization may be 0.300 or smaller.
Inventors:
NEGISHI JUN (JP)
HIWATARI KEN-ICHIRO (JP)
OCHIAI KYOHEI (JP)
HIWATARI KEN-ICHIRO (JP)
OCHIAI KYOHEI (JP)
Application Number:
PCT/JP2016/054911
Publication Date:
September 01, 2016
Filing Date:
February 19, 2016
Export Citation:
Assignee:
ADEKA CORP (JP)
International Classes:
A61L27/00; A61K35/12; A61P43/00
Domestic Patent References:
| WO2014181886A1 | 2014-11-13 | |||
| WO2014013241A1 | 2014-01-23 | |||
| WO2005063316A1 | 2005-07-14 |
Foreign References:
| JP2010227246A | 2010-10-14 | |||
| JP2010504093A | 2010-02-12 | |||
| JP2007301262A | 2007-11-22 | |||
| JP2015160039A | 2015-09-07 | |||
| JP2015160040A | 2015-09-07 |
Other References:
NGANGAN. A. V. ET AL.: "Acellularization of embryoid bodies via physical disruption methods", BIOMATERIALS, vol. 30, no. 6, 2009, pages 1143 - 1149, XP025840059, DOI: doi:10.1016/j.biomaterials.2008.11.001
See also references of EP 3263140A4
See also references of EP 3263140A4
Attorney, Agent or Firm:
SHOBAYASHI, Masayuki et al. (JP)
Right wood Masayuki (JP)
Right wood Masayuki (JP)
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