DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM

Title:

DEGRADABLE HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) ACRYLATES AND GELS AND CONJUGATES DERIVED THEREFROM

Document Type and Number:

WIPO Patent Application WO1999034833

Kind Code:

A9

Abstract:

A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coupling to a target. Hydrogels can be prepared. The hydrogels can be used as a carrier for a protein or a pharmaceutical agent that can be readily released in a controlled fashion.

Inventors:

HARRIS J MILTON (US)
ZHAO XUAN (US)

Application Number:

PCT/US1999/000594

Publication Date:

March 17, 2005

Filing Date:

January 06, 1999

Export Citation:

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Assignee:

SHEARWATER POLYMERS INC (US)
HARRIS J MILTON (US)
ZHAO XUAN (US)

International Classes:

A61K47/48; C08F299/00; C08G65/329; C08G81/00; (IPC1-7): A61K47/48

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