Title:
DEGRADABLE POLYMER AND PROCESS FOR PRODUCTION THEREOF
Document Type and Number:
WIPO Patent Application WO/2006/121007
Kind Code:
A1
Abstract:
Disclosed is a degradable polymer having a peroxide bond therein which can be utilized in the fields of medicals or medical materials, can be applied to a DDS or gene delivery system and can be used as a novel polymeric material or environment-friendly material. A polyperoxide (114), which is an alternating copolymer, having a functional group (112) which is a substituent comprising a therapeutic molecule, a water-soluble substituent or a biodegradable substituent in a side chain thereof.
Inventors:
MATSUMOTO AKIKAZU
Application Number:
PCT/JP2006/309252
Publication Date:
November 16, 2006
Filing Date:
May 08, 2006
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
OSAKA IND PROMOTION ORG (JP)
MATSUMOTO AKIKAZU
OSAKA IND PROMOTION ORG (JP)
MATSUMOTO AKIKAZU
International Classes:
C08G67/00; A61K47/48; C08L101/16
Domestic Patent References:
| WO2004087791A1 | 2004-10-14 |
Foreign References:
| US20040087791A1 | 2004-05-06 | |||
| US20030065023A1 | 2003-04-03 |
Other References:
HATAKENAKA H. ET AL.: "Degradable Polymers Prepared from Alkyl Sorbates and Oxygen Under Atmospheric Conditions and Precise Evaluation of Their Thermal Properties", POLYMER JOURNAL, vol. 35, no. 8, 2003, pages 640 - 651, XP001175936
MATSUMOTO A. ET AL.: "Fabrication and Degradation of Polyperoxides by a Radical Chain Process under Mild Conditions", CHEMISTRY LETTERS, vol. 33, no. 6, 2004, pages 732 - 733, XP003002776
TAKETANI S. ET AL.: "Facile Synthesis of a Degradable Gel by Radical Copolymerization of Vinyl Sorbate and Molecular Oxygen", MACROMOLECULAR CHEMISTRY AND PHYSICS, vol. 205, no. 18, 2004, pages 2451 - 2456, XP003002777
See also references of EP 1897898A4
"Radical Alternating Copolymerization of Sorbic Esters and Oxygen in the Solid State Under Photoirradiation", DIGEST OF THE 44TH ANNUAL MEETING OF THE SOCIETY OF POLYMER SCIENCE, JAPAN, 10 July 1998 (1998-07-10), pages 13
"Database WPI", Database accession no. 198607
K.A.H. CHEHADE ET AL.: "Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase", JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 124, no. 28, 2001, pages 8206 - 8219
H. HATAKENAKA ET AL.: "Degradable polymers prepared from alkyl sorbates and oxygen under atmospheric conditions and precise evaluation of their thermal properties", POLYMER JOURNAL, vol. 35, no. 8, 2003, pages 640 - 651
A. MATSUMOTO ET AL.: "Fabrication and degradation of polyperoxides by a radical chain process under mild conditions", CHEMISTRY LETTERS, vol. 33, no. 6, 2004, pages 732 - 733
S. TAKETANI ET AL.: "Facile synthesis of a degradable gel by radical copolymerization of vinyl sorbate and molecular oxygen", MACROMOLECULAR CHEMISTRY AND PHYSICS, vol. 205, 2004, pages 2451 - 2456
MATSUMOTO A. ET AL.: "Fabrication and Degradation of Polyperoxides by a Radical Chain Process under Mild Conditions", CHEMISTRY LETTERS, vol. 33, no. 6, 2004, pages 732 - 733, XP003002776
TAKETANI S. ET AL.: "Facile Synthesis of a Degradable Gel by Radical Copolymerization of Vinyl Sorbate and Molecular Oxygen", MACROMOLECULAR CHEMISTRY AND PHYSICS, vol. 205, no. 18, 2004, pages 2451 - 2456, XP003002777
See also references of EP 1897898A4
"Radical Alternating Copolymerization of Sorbic Esters and Oxygen in the Solid State Under Photoirradiation", DIGEST OF THE 44TH ANNUAL MEETING OF THE SOCIETY OF POLYMER SCIENCE, JAPAN, 10 July 1998 (1998-07-10), pages 13
"Database WPI", Database accession no. 198607
K.A.H. CHEHADE ET AL.: "Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase", JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 124, no. 28, 2001, pages 8206 - 8219
H. HATAKENAKA ET AL.: "Degradable polymers prepared from alkyl sorbates and oxygen under atmospheric conditions and precise evaluation of their thermal properties", POLYMER JOURNAL, vol. 35, no. 8, 2003, pages 640 - 651
A. MATSUMOTO ET AL.: "Fabrication and degradation of polyperoxides by a radical chain process under mild conditions", CHEMISTRY LETTERS, vol. 33, no. 6, 2004, pages 732 - 733
S. TAKETANI ET AL.: "Facile synthesis of a degradable gel by radical copolymerization of vinyl sorbate and molecular oxygen", MACROMOLECULAR CHEMISTRY AND PHYSICS, vol. 205, 2004, pages 2451 - 2456
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (2-6 Tenjinbashi 2-chome Kit, Kita-ku Osaka-shi Osaka 41, JP)
Download PDF: