Title:
DEHYDROABIETIC ACID (DHAA) DERIVATIVES FOR USE AS ION CHANNEL OPENERS
Document Type and Number:
WIPO Patent Application WO/2016/114707
Kind Code:
A8
Abstract:
The present invention relates to derivatives of dehydroabietic acid useful in treatment ofcardiac arrhythmiaor a hyperexcitablity disease, such as epilepsy or pain, by extracellularly acting on the voltage sensitive domain (VSD) to open atleast one member of the family of voltage-gated Kv (potassium) channels.
Inventors:
ELINDER FREDRIK (SE)
KONRADSSON PETER (SE)
LIIN SARA (SE)
OTTOSSON NINA (SE)
XIONGYU WU (SE)
KONRADSSON PETER (SE)
LIIN SARA (SE)
OTTOSSON NINA (SE)
XIONGYU WU (SE)
Application Number:
PCT/SE2016/050008
Publication Date:
September 29, 2016
Filing Date:
January 11, 2016
Export Citation:
Assignee:
ELINDER FREDRIK (SE)
KONRADSSON PETER (SE)
LIIN SARA (SE)
OTTOSSON NINA (SE)
XIONGYU WU (SE)
KONRADSSON PETER (SE)
LIIN SARA (SE)
OTTOSSON NINA (SE)
XIONGYU WU (SE)
International Classes:
C07C61/40; A61K31/19; A61P9/06; A61P25/08; C07C251/34; C07C251/36; C07C251/40
Attorney, Agent or Firm:
BERGENSTRÅHLE & PARTNERS STOCKHOLM AB (SE)
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