DENDRITIC CELL IMMUNE RECEPTOR ACTIVATOR, METHOD FOR ACTIVATING DENDRITIC CELL IMMUNE RECEPTOR, OSTEOCLAST FORMATION INHIBITOR, METHOD FOR INHIBITING OSTEOCLAST FORMATION, DENDRITIC CELL DIFFERENTIATION/PROLIFERATION INHIBITOR, METHOD FOR INHIBITING DENDRITIC CELL DIFFERENTIATION/PROLIFERATION, CYTOKINE PRODUCTION INHIBITOR, METHOD FOR INHIBITING CYTOKINE PRODUCTION, THERAPEUTIC METHOD, AND SCREENING METHOD

Title:

Document Type and Number:

WIPO Patent Application WO/2016/006700

Kind Code:

A1

Abstract:

　Provided are: a dendritic cell immune receptor activator, containing as an active ingredient a compound comprising a sugar chain having as a basic structure the structure represented in the formula (where there is no sialic acid present on the two non-reducing terminals of the structure, and x and y independently represent 3 or 4); a method for activating dendritic cell immune receptors; an osteoclast formation inhibitor; a method for inhibiting osteoclast formation; a dendritic cell differentiation/proliferation inhibitor; a method for inhibiting dendritic cell differentiation/proliferation; a cytokine production inhibitor; a method for inhibiting cytokine production; a therapeutic method and a screening method.

More Like This:

WO/1996/040168	USE OF HYDROXYETHYL STARCH TO PREVENT POST SURGICAL ADHESION AND AS AN INTRACAVITY CARRIER DEVICE
JP2753726	INDUSTRIAL APPLICABILITY [Title of Invention] Low-molecular-weight guar gum, a method for producing the same, and foods and drinks containing the same.

Inventors:

IWAKURA YOICHIRO (JP)
KAIFU TOMONORI (JP)
YABE RIKIO (JP)

Application Number:

PCT/JP2015/069960

Publication Date:

January 14, 2016

Filing Date:

July 10, 2015

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV TOKYO SCIENCE FOUNDATION (JP)

International Classes:

A61K31/715; A61P19/10; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C12N15/09; G01N33/15; G01N33/50

Domestic Patent References:

WO2011105424A1	2011-09-01
WO2008001498A1	2008-01-03
WO1996002255A1	1996-02-01

Foreign References:

JP2007508328A	2007-04-05
JP2000139463A	2000-05-23

Other References:

RIBOLDI E. ET AL.: "Human C-type Lectin Domain Family 4, Member C (CLEC4C/BDCA-2/ CD 303) Is a Receptor for Asialo-galactosyl-oligosaccharides", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 286, no. 41, 2011, pages 35329 - 35333, XP055250296, ISSN: 0021-9258
RIKIO YABE ET AL.: "DC-SIGN Kanren Lectin no Teiryoteki Sogo Sayo Kaiseki: Agalacto N-gata Tosa eno Shinki Tokuisei no Hakken", JOURNAL OF JAPANESE BIOCHEMICAL SOCIETY, 2009, pages ROMBUNN0. 4P-10 8, XP008183687
See also references of EP 3167889A4

Attorney, Agent or Firm:

NAKAJIMA, Jun et al. (JP)
Nakajima 淳 (JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: LAMP

Next Patent: METHOD FOR PRODUCING AQUEOUS OPHTHALMIC COMPOSITION, AND AQUEOUS OPHTHALMIC COMPOSITION