Title:
DENGUE-VIRUS SEROTYPE NEUTRALIZING ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/2013/035345
Kind Code:
A2
Abstract:
Materials and methods are provided for treating dengue infections. Human monoclonal antibodies against all serotypes of dengue virus are also provided. Methods of using human monoclonal antibodies to neutralize all dengue-virus serotypes are provided using patients' peripheral blood lymphocytes.
Inventors:
SETTHAPRAMOTE CHAYANEE (TH)
SASAKI TADAHIRO (JP)
KUHARA MOTOKI (JP)
RAMASOOTA PONGRAMA (TH)
THATTIYAPHONG AREE (TH)
ANANTAPREECHA SURAPEE (TH)
SAWANPANYALERT PATHOM (TH)
OKUNO YOSHINOBU (JP)
IKUTA KAZUYOSHI (JP)
A-NUEGOONPIPAT ATCHAREEYA (TH)
DHEPAKSON PANADDA (TH)
PRACHASUPHAP APICHAI (TH)
SASAKI TADAHIRO (JP)
KUHARA MOTOKI (JP)
RAMASOOTA PONGRAMA (TH)
THATTIYAPHONG AREE (TH)
ANANTAPREECHA SURAPEE (TH)
SAWANPANYALERT PATHOM (TH)
OKUNO YOSHINOBU (JP)
IKUTA KAZUYOSHI (JP)
A-NUEGOONPIPAT ATCHAREEYA (TH)
DHEPAKSON PANADDA (TH)
PRACHASUPHAP APICHAI (TH)
Application Number:
PCT/JP2012/005699
Publication Date:
March 14, 2013
Filing Date:
September 07, 2012
Export Citation:
Assignee:
UNIV OSAKA (JP)
UNIV OSAKA RES FOUND (JP)
MEDICAL & BIOL LAB CO LTD (JP)
UNIV MAHIDOL (TH)
DEPT OF MEDICAL SCIENCES DMSC (TH)
SETTHAPRAMOTE CHAYANEE (TH)
SASAKI TADAHIRO (JP)
KUHARA MOTOKI (JP)
RAMASOOTA PONGRAMA (TH)
THATTIYAPHONG AREE (TH)
ANANTAPREECHA SURAPEE (TH)
SAWANPANYALERT PATHOM (TH)
OKUNO YOSHINOBU (JP)
IKUTA KAZUYOSHI (JP)
A-NUEGOONPIPAT ATCHAREEYA (TH)
DHEPAKSON PANADDA (TH)
PRACHASUPHAP APICHAI (TH)
UNIV OSAKA RES FOUND (JP)
MEDICAL & BIOL LAB CO LTD (JP)
UNIV MAHIDOL (TH)
DEPT OF MEDICAL SCIENCES DMSC (TH)
SETTHAPRAMOTE CHAYANEE (TH)
SASAKI TADAHIRO (JP)
KUHARA MOTOKI (JP)
RAMASOOTA PONGRAMA (TH)
THATTIYAPHONG AREE (TH)
ANANTAPREECHA SURAPEE (TH)
SAWANPANYALERT PATHOM (TH)
OKUNO YOSHINOBU (JP)
IKUTA KAZUYOSHI (JP)
A-NUEGOONPIPAT ATCHAREEYA (TH)
DHEPAKSON PANADDA (TH)
PRACHASUPHAP APICHAI (TH)
International Classes:
A61K39/00; C07K16/10
Domestic Patent References:
| WO1994011026A2 | 1994-05-26 | |||
| WO1993011161A1 | 1993-06-10 |
Foreign References:
| US4741900A | 1988-05-03 | |||
| US5169939A | 1992-12-08 | |||
| US5750078A | 1998-05-12 | |||
| US6020153A | 2000-02-01 | |||
| US6420113B1 | 2002-07-16 | |||
| US6423511B1 | 2002-07-23 | |||
| US6632927B2 | 2003-10-14 | |||
| US6800738B1 | 2004-10-05 | |||
| US4816567A | 1989-03-28 | |||
| EP0404097A2 | 1990-12-27 | |||
| US5643759A | 1997-07-01 | |||
| US4485045A | 1984-11-27 | |||
| US4544545A | 1985-10-01 | |||
| US5013556A | 1991-05-07 | |||
| US4450150A | 1984-05-22 |
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SHOJI, Takashi et al. (5-6-13 Nishinakajima, Yodogawa-ku, Osaka-sh, Osaka 11, JP)
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