DENTAL CARE COMPOSITION AND METHOD FOR PROMOTING CALCIFICATION IN BIOLOGICAL TISSUES

Title:

DENTAL CARE COMPOSITION AND METHOD FOR PROMOTING CALCIFICATION IN BIOLOGICAL TISSUES

Document Type and Number:

WIPO Patent Application WO/2022/138774

Kind Code:

A1

Abstract:

A dental care composition comprising an isothiocyanate having: an isothiocyanate group (-N=C=S); and a sulfinyl group (-S(=O)-), a sulfonyl group (-S(=O)2-), a sulfide bond (-S-), or an aryl group. A composition used for promoting activation of a reaction catalyzed by a carbonic anhydrase and activation of a TRPA1 channel.

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Inventors:

OKUNISHI ISAO (JP)
SHIBUKAWA YOSHIYUKI (JP)
KIMURA MAKI (JP)

Application Number:

PCT/JP2021/047722

Publication Date:

June 30, 2022

Filing Date:

December 22, 2021

Export Citation:

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Assignee:

KINJIRUSHI CO LTD (JP)
TOKYO DENTAL COLLEGE (JP)

International Classes:

A61Q11/00; A23G3/34; A23G4/12; A23L33/105; A61K8/46

Domestic Patent References:

WO2018124258A1	2018-07-05
WO2014181724A1	2014-11-13
WO2018066707A1	2018-04-12

Foreign References:

KR20030064902A	2003-08-06
JPH01311009A	1989-12-15
JP2009155334A	2009-07-16
JP2015231953A	2015-12-24

Other References:

KIMURA M., SASE T., HIGASHIKAWA A., SATO M., SATO T., TAZAKI M., SHIBUKAWA Y.: "High pH–Sensitive TRPA1 Activation in Odontoblasts Regulates Mineralization", JOURNAL OF DENTAL RESEARCH, INTERNATIONAL ASSOCIATION FOR DENTAL RESEARCH, US, vol. 95, no. 9, 1 August 2016 (2016-08-01), US , pages 1057 - 1064, XP055947018, ISSN: 0022-0345, DOI: 10.1177/0022034516644702

Attorney, Agent or Firm:

NAGOYA INTERNATIONAL PATENT FIRM (JP)

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