Title:
DEOXYCHOLIC ACID DERIVATIVES FOR THE TREATMENT OF ACUTE DYSFUNCTIONS OF PORTAL AND HEPATIC VENOUS CIRCULATION
Document Type and Number:
WIPO Patent Application WO2003095471
Kind Code:
A3
Abstract:
Use of compounds and their salts of formula (I), as reported in the description, in the preparation of drugs for the treatment of acute dysfunctions of portal and hepatic venous circulation.
Inventors:
DEL SOLDATO PIERO (IT)
ACUTO GIANCARLO (IT)
ACUTO GIANCARLO (IT)
Application Number:
PCT/EP2003/004861
Publication Date:
April 01, 2004
Filing Date:
May 09, 2003
Export Citation:
Assignee:
NICOX SA (FR)
DEL SOLDATO PIERO (IT)
ACUTO GIANCARLO (IT)
DEL SOLDATO PIERO (IT)
ACUTO GIANCARLO (IT)
International Classes:
A61K31/575; A61K31/58; A61P1/16; A61P9/00; C07J41/00; (IPC1-7): C07J41/00; A61K31/575; A61K31/58; A61P1/16
Domestic Patent References:
| WO2000061604A2 | 2000-10-19 |
Other References:
MIYAIRI S ET AL: "PREPARATION OF NEW HAPTENS FOR USE IN IMMUNOASSAY OF GLYCINE CONJUGATED BILE ACIDS", CHEMICAL & PHARMACEUTICAL BULLETIN (TOKYO), vol. 32, no. 5, 1984, pages 1891 - 1897, XP001154974, ISSN: 0009-2363
POO J L ET AL: "URSODEOXYCHOLIC ACID LIMITS LIVER HISTOLOGIC ALTERATIONS AND PORTAL HYPERTENSION INDUCED BY BILE DUCT LIGATION IN THE RAT", GASTROENTEROLOGY, vol. 102, no. 5, 1992, pages 1752 - 1759, XP009017793, ISSN: 0016-5085
KARRER F M: "Portal hypertension.", SEMINARS IN PEDIATRIC SURGERY. UNITED STATES MAY 1992, vol. 1, no. 2, May 1992 (1992-05-01), pages 134 - 144, XP009017761, ISSN: 1055-8586
POO J L ET AL: "URSODEOXYCHOLIC ACID LIMITS LIVER HISTOLOGIC ALTERATIONS AND PORTAL HYPERTENSION INDUCED BY BILE DUCT LIGATION IN THE RAT", GASTROENTEROLOGY, vol. 102, no. 5, 1992, pages 1752 - 1759, XP009017793, ISSN: 0016-5085
KARRER F M: "Portal hypertension.", SEMINARS IN PEDIATRIC SURGERY. UNITED STATES MAY 1992, vol. 1, no. 2, May 1992 (1992-05-01), pages 134 - 144, XP009017761, ISSN: 1055-8586
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