PRECISION/CONTEXT-DEPENDENT ACTIVATABLE ANTIBODIES, AND METHODS OF MAKING AND USING THE SAME

Title:

PRECISION/CONTEXT-DEPENDENT ACTIVATABLE ANTIBODIES, AND METHODS OF MAKING AND USING THE SAME

Document Type and Number:

WIPO Patent Application WO/2019/148445

Kind Code:

A1

Abstract:

Provided herein are libraries containing synthetic polynucleotides that encode activatable binding polypeptides. Further provided herein are activatable binding polypeptides and polypeptide libraries containing such activatable binding polypeptides. Also provided herein are vectors, vector libraries, cells, kits, and methods of making and using activatable polypeptide libraries.

Inventors:

LUO PETER (CN)
DU FANGYONG (CN)

Application Number:

PCT/CN2018/075065

Publication Date:

August 08, 2019

Filing Date:

February 02, 2018

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Assignee:

ADAGENE INC (KY)
LUO PETER PEIZHI (CN)

International Classes:

C40B40/08; A61P35/00; C07K19/00; C12N1/15; C12N1/21; C12N5/16; C40B30/06; C40B40/10

Domestic Patent References:

WO2010081173A2

2010-07-15

Foreign References:

CN106163556A

2016-11-23

Attorney, Agent or Firm:

WU, FENG & ZHANG (CN)

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