Title:
DERIVATIVES OF THAILANSTATIN A, METHODS OF TREATMENT AND METHODS OF SYNTHESIS THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/214423
Kind Code:
A8
Abstract:
In one aspect, the present disclosure provides analogs of thailanstatin of the formula wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.
Inventors:
NICOLAOU KYRIACOS C (US)
RHOADES DEREK (US)
KUMAR SOUNDARAPANDIAN M (US)
PATTANAYAK MANAS R (US)
LAMANI MANJUNATH (US)
RHOADES DEREK (US)
KUMAR SOUNDARAPANDIAN M (US)
PATTANAYAK MANAS R (US)
LAMANI MANJUNATH (US)
Application Number:
PCT/US2017/036589
Publication Date:
April 05, 2018
Filing Date:
June 08, 2017
Export Citation:
Assignee:
UNIV RICE WILLIAM M (US)
International Classes:
C07D491/052; C07D498/18; C12P17/18
Attorney, Agent or Firm:
LONG, Reid, S. (US)
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