Title:
DESENSITIZERS
Document Type and Number:
WIPO Patent Application WO/2003/020306
Kind Code:
A1
Abstract:
Allergic reaction suppressors comprising a peptide which originates in the same antigenic substance as the antigenic substance inducing the allergic reaction, contains an epitope different from the epitope participating in the induction of the allergic reaction and yet does not induce the allergic reaction&semi preventives and&sol or remedies or medicinal compositions for type I allergic diseases containing the above suppressors&semi a method of suppressing allergic reactions, a desensitizing method, and a method of preventing&sol treating type I allergic diseases with the use of the same&semi a cancer vaccine containing a tumor rejection antigen−origin peptide which has a cytotoxic T lymphocyte inducing activity but inducing an allergy reaction and another peptide which originates in the same antigen as the above peptide, has an epitope different from the epitope of the above peptide and exhibits an effect of suppressing the allergic reaction&semi remedies for cancer containing the above vaccine&semi and a method of treating cancer with the use of the vaccine.
Inventors:
ITOH KYOGO (JP)
YAMADA AKIRA (JP)
YAMADA AKIRA (JP)
Application Number:
PCT/JP2002/008641
Publication Date:
March 13, 2003
Filing Date:
August 28, 2002
Export Citation:
Assignee:
ITOH KYOGO (JP)
YAMADA AKIRA (JP)
YAMADA AKIRA (JP)
International Classes:
A61K38/16; A61K38/17; A61K38/52; A61K39/00; A61K39/35; A61P35/00; A61P37/08; (IPC1-7): A61K39/00; A61K38/00; A61P35/00; A61P37/08
Domestic Patent References:
| WO1999022762A1 | 1999-05-14 | |||
| WO1999058552A2 | 1999-11-18 |
Foreign References:
| EP0700929A2 | 1996-03-13 | |||
| JPH1192497A | 1999-04-06 |
Other References:
TAKAI TOSHIRO ET AL.: "Non-anaphylactic combination of partially deleted fragments of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy", MOLECULAR IMMUNOLOGY, vol. 36, no. 15-16, October 1999 (1999-10-01) - November 1999 (1999-11-01), pages 1055 - 1065, XP001024190
NOBUE IMAI ET AL.: "Peptide vaccine ni yoru kodo shinko haigan no men'ekigaku-teki hyoka", BIOTHERAPY, vol. 15, no. 3, 30 May 2001 (2001-05-30), pages 293, XP002962385
TAKASHI MINE ET AL.: "Gan peptide vaccine dai I so shiken no chukan kaiseki", BIOTHERAPY, vol. 15, no. 3, 30 May 2001 (2001-05-30), pages 181, XP002962386
See also references of EP 1430904A4
NOBUE IMAI ET AL.: "Peptide vaccine ni yoru kodo shinko haigan no men'ekigaku-teki hyoka", BIOTHERAPY, vol. 15, no. 3, 30 May 2001 (2001-05-30), pages 293, XP002962385
TAKASHI MINE ET AL.: "Gan peptide vaccine dai I so shiken no chukan kaiseki", BIOTHERAPY, vol. 15, no. 3, 30 May 2001 (2001-05-30), pages 181, XP002962386
See also references of EP 1430904A4
Attorney, Agent or Firm:
Shoji, Takashi (2-10 Iwamotocho 3-chom, Chiyoda-ku Tokyo, JP)
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