Title:
DETECTION OF HIV-RELATED PROTEINS IN URINE
Document Type and Number:
WIPO Patent Application WO/2010/042425
Kind Code:
A3
Abstract:
A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HFV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
Inventors:
NEWMAN GALE W (US)
POWELL MIKE (US)
DOHERTY AKINS (US)
OBIALO CHAMBERLAIN (US)
MITCHELL-ALI CLAUDETTE (UA)
BASHIR KHALID (US)
KHAN MAFUZ (US)
POWELL MIKE (US)
DOHERTY AKINS (US)
OBIALO CHAMBERLAIN (US)
MITCHELL-ALI CLAUDETTE (UA)
BASHIR KHALID (US)
KHAN MAFUZ (US)
Application Number:
PCT/US2009/059500
Publication Date:
July 22, 2010
Filing Date:
October 05, 2009
Export Citation:
Assignee:
MOREHOUSE SCHOOL OF MEDICINE (US)
NEWMAN GALE W (US)
POWELL MIKE (US)
DOHERTY AKINS (US)
OBIALO CHAMBERLAIN (US)
MITCHELL-ALI CLAUDETTE (UA)
BASHIR KHALID (US)
KHAN MAFUZ (US)
NEWMAN GALE W (US)
POWELL MIKE (US)
DOHERTY AKINS (US)
OBIALO CHAMBERLAIN (US)
MITCHELL-ALI CLAUDETTE (UA)
BASHIR KHALID (US)
KHAN MAFUZ (US)
International Classes:
G01N33/68; G01N33/493
Other References:
THE JOURNAL OF CELL BIOLOGY, vol. 172, no. 6, 2006, pages 923 - 935, XP008136118
PLOS BIOLOGY, E158, vol. 5, no. 6, 2007, pages 1267 - 1283, XP008136116
TRENDS IN MICROBIOLOGY, vol. 12, no. 7, 2004, pages 310 - 316, XP002570031
IMMUNOLOGY LETTERS, vol. 107, 2006, pages 102 - 108, XP024999091
PLOS BIOLOGY, E158, vol. 5, no. 6, 2007, pages 1267 - 1283, XP008136116
TRENDS IN MICROBIOLOGY, vol. 12, no. 7, 2004, pages 310 - 316, XP002570031
IMMUNOLOGY LETTERS, vol. 107, 2006, pages 102 - 108, XP024999091
Attorney, Agent or Firm:
WANG, Ping, M.D. (Manning & Martin, LLP,1333 H Street, NW,Suite 82, Washington DC, US)
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