Title:
DEVELOPMENT OF PLURIPOTENT STEM CELL EMPLOYING NOVEL DEDIFFERENTIATION INDUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2014/097875
Kind Code:
A1
Abstract:
The purpose of the present invention is to obtain: a novel pluripotent stem cell production method; or a therapeutic agent for malignant tumors. A method for inducing the dedifferentiation of a cell, which involves a step of inhibiting the expression or function of a miR-520d-5p-controlled gene, is employed. Or, a therapeutic agent for malignant tumors, which comprises an inhibitor of the expression or function of the miR-520d-5p-controlled gene, is used.
Inventors:
MIURA NORIMASA (JP)
Application Number:
PCT/JP2013/082399
Publication Date:
June 26, 2014
Filing Date:
December 02, 2013
Export Citation:
Assignee:
NAT UNIV CORP TOTTORI UNIV (JP)
International Classes:
C12N15/113; A61K31/7105; A61K35/12; A61K45/00; A61L27/00; A61P35/00; C12N5/10; A61K35/545
Domestic Patent References:
| WO2010108126A2 | 2010-09-23 | |||
| WO2009045443A2 | 2009-04-09 | |||
| WO2011146879A2 | 2011-11-24 | |||
| WO2003007793A2 | 2003-01-30 | |||
| WO2008008472A2 | 2008-01-17 | |||
| WO2004056386A2 | 2004-07-08 |
Foreign References:
| JP2010536367A | 2010-12-02 |
Other References:
KNIGHT J.F. ET AL.: "TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer", BRITISH JOURNAL OF CANCER, vol. 99, no. 11, 2008, pages 1849 - 1858
Attorney, Agent or Firm:
SK INTELLECTUAL PROPERTY LAW FIRM et al. (JP)
SK patent business corporation (JP)
SK patent business corporation (JP)
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