Title:
DEVELOPMENT OF SPECIFIC IMMUNOASSAY CRITICAL REAGENTS FOR PHARMACOKINETIC ASSESSMENTS OF PEPTIDE POLYMERS IN PRECLINICAL AND CLINICAL MATRICES
Document Type and Number:
WIPO Patent Application WO/2013/088348
Kind Code:
A3
Abstract:
The present disclosure provides methods of developing a specific immunoassay for the Pharmacokinetic assessments of peptides, peptide oligomer and polymer including Glatiramer Acetate (GA), also known as Copolymer 1, Copolymer- 1, Cop 1 or Cop in the clinical and preclinical matrices.
Inventors:
MURGANANDAM ARUMUGAM (IN)
CHIKKEGOWDA BINDU (IN)
RAJU KONDA VENKATA NARASIMHA (IN)
SRIPADRAO SRIKANTH (IN)
MURALIDHARAN SANTHARAM (IN)
SUBRAMANI THANGAMMA KUNJIRA (IN)
SHIVANNA NAVYA (IN)
CHIKKEGOWDA BINDU (IN)
RAJU KONDA VENKATA NARASIMHA (IN)
SRIPADRAO SRIKANTH (IN)
MURALIDHARAN SANTHARAM (IN)
SUBRAMANI THANGAMMA KUNJIRA (IN)
SHIVANNA NAVYA (IN)
Application Number:
PCT/IB2012/057200
Publication Date:
August 08, 2013
Filing Date:
December 12, 2012
Export Citation:
Assignee:
BIOCON LTD (IN)
International Classes:
C07K16/06; G01N33/50; C07K16/44
Foreign References:
| US20020182210A1 | 2002-12-05 |
Other References:
URE ET AL.: "Polyreactive antibodies to glatiramer acetate promote myelin repair in murine model of demyelinating disease", FASEB JOURNAL., vol. 16, no. 10, August 2002 (2002-08-01), pages 1260 - 1262, XP002339150
MELCHIOR F: "Generation and purification of rabbit or goat polyclonal antibodies", RUBICON, pages 3 - 6, XP008175695, Retrieved from the Internet
HAGE D: "Affinity chromatography: a review of clinical applications", CLIN CHEM., vol. 45, no. 5, May 1999 (1999-05-01), pages 593 - 615, XP001120858
LAFFEY B: "Monoclonal Antibodies to Bovine Serum Albumin: Affinity Purification and Physiochemical Characterization", MASSACHUSETTS INSTITUTE OF TECHNOLOGY, 1995, XP055156867
MELCHIOR F: "Generation and purification of rabbit or goat polyclonal antibodies", RUBICON, pages 3 - 6, XP008175695, Retrieved from the Internet
HAGE D: "Affinity chromatography: a review of clinical applications", CLIN CHEM., vol. 45, no. 5, May 1999 (1999-05-01), pages 593 - 615, XP001120858
LAFFEY B: "Monoclonal Antibodies to Bovine Serum Albumin: Affinity Purification and Physiochemical Characterization", MASSACHUSETTS INSTITUTE OF TECHNOLOGY, 1995, XP055156867
Attorney, Agent or Firm:
MUKHARYA, Durgesh et al. (6th Cross 19th A Main,,Hal II Stage, Bangalore Karnataka 8, IN)
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