Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
DEVICE FOR A CONTINUOUS VIRUS INACTIVATION
Document Type and Number:
WIPO Patent Application WO/2022/200280
Kind Code:
A8
Abstract:
The invention relates to a device for a continuous virus inactivation during a protein production process, comprising a first and a second fluid inlet (2, 3), each of which is designed to introduce a liquid flow into the device (1), comprising a first mixer (4), which is designed to mix a liquid flow, and comprising a fluid outlet (5), which is designed to discharge a liquid flow out of the device (1), wherein a first liquid flow (6) which contains a target protein can be introduced into the device (1) by the first fluid inlet (2) and can be combined with a second virus-inactivating liquid flow (7), which can be introduced into the device (1) by the second fluid inlet (3), in a precisely defined volume ratio in order to form a third reactive liquid flow (8) which is conducted through the first mixer (4) for mixing purposes in order to generate defined virus-inactivating conditions. According to the invention, the device (1) has a head part (9) for combining two liquid flows, one of which is the liquid flow (6) containing the target protein; the device (1) has a dwell time assembly (10), which is fluidically connected to the head part (9), downstream of the first mixer (4) and upstream of the fluid outlet (5) in order to provide a minimum dwell time of the third reactive liquid flow (8) within the device (1); the head part (9) and the dwell time assembly (10) are rigidly secured to each other; and end face of the head part (9) is arranged on the dwell time assembly (10).

More Like This:
JP2023502925Polymer-encapsulated viral vectors for in vivo gene therapy
WO/2018/210266FLEXURE-GUIDED PIEZO DRILL WITH LARGE AXIAL VIBRATION AND SMALL LATERAL VIBRATION
JP2011234671NUCLEIC ACID EXTRACTION DEVICE
Inventors:
SCHÄFER JAN (DE)
WEISSHAAR STEFAN (DE)
HELLING ALEXANDER (DE)
DEUSE MARIO (DE)
DIEL BERNHARD (DE)
TAPPE ALEXANDER (DE)
Application Number:
PCT/EP2022/057365
Publication Date:
November 09, 2023
Filing Date:
March 21, 2022
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SARTORIUS STEDIM BIOTECH GMBH (DE)
International Classes:
C12M1/00; B01F25/42; B01F25/43; C07K1/14; C07K1/36
Attorney, Agent or Firm:
GOTTSCHALD PATENTANWÄLTE PARTNERSCHAFT MBB (DE)
Download PDF:
View/Download PDF      PDF Help



 
Previous Patent: TEMPERATURE MONITORING PROCESS FOR SWITCHGEARS

Next Patent: RECONFIGURABLE REFLECTIVE DEVICE