Title:
DEVICE FOR CREATING A PATTERNED EVANESCENT FIELD ON A SURFACE AND ASSOCIATED METHOD
Document Type and Number:
WIPO Patent Application WO/2020/230051
Kind Code:
A1
Abstract:
The invention concerns a device (1) for creating a patterned evanescent field on the surface (S) of a dioptre, said device comprising: a lens (O), the surface (S) of the dioptre being disposed in an image focal plane of said lens; a light-injection element (2) emitting a collimated light beam (B); an optical assembly (4) between the element (2) and the lens (O), by means of which the object plane of the lens (O) is optically conjugate with the image plane of the element (2), the assembly (4) being configured such that a collimated light beam (B) originating from the element (4) is emitted towards the lens (O) so as to be deflected towards the surface (S) of the dioptre with an angle of incidence greater than or equal to the critical angle of the dioptre; and an optical device (FS1) for forming patterns in the object plane of the element (2), such that the pattern formed by the optical device for forming patterns in light transmitted on the light beam in the object plane of the element (2) is found on the surface of the dioptre.
Inventors:
GRICHINE ALEXEI (FR)
DESTAING OLIVIER (FR)
DESTAING OLIVIER (FR)
Application Number:
PCT/IB2020/054529
Publication Date:
November 19, 2020
Filing Date:
May 13, 2020
Export Citation:
Assignee:
UNIV GRENOBLE ALPES (FR)
CENTRE NAT RECH SCIENT (FR)
CENTRE NAT RECH SCIENT (FR)
International Classes:
G02B21/08; G01N21/64; G02B21/16; G02B27/56
Foreign References:
| US20160131885A1 | 2016-05-12 | |||
| US20120319007A1 | 2012-12-20 | |||
| JP2016061967A | 2016-04-25 | |||
| US20170276922A1 | 2017-09-28 | |||
| US20160131885A1 | 2016-05-12 | |||
| US20120319007A1 | 2012-12-20 |
Other References:
P. KNER ET AL: "Live TIRF microscopy at 100nm resolution through structured illumination", PROCEEDINGS OF SPIE, vol. 7184, 12 February 2009 (2009-02-12), 1000 20th St. Bellingham WA 98225-6705 USA, pages 718417, XP055661376, ISSN: 0277-786X, ISBN: 978-1-5106-2687-4, DOI: 10.1117/12.812351
LAURENCE J. YOUNG ET AL: "A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors", JOURNAL OF VISUALIZED EXPERIMENTS, no. 111, 30 May 2016 (2016-05-30), XP055607172, DOI: 10.3791/53988
FIOLKA R ET AL: "Structured illumination in total internal reflection fluorescence microscopy using a spatial light modulator", OPTICS LETTERS, OPTICAL SOCIETY OF AMERICA, US, vol. 33, no. 14, 15 July 2008 (2008-07-15), pages 1629 - 1631, XP001514976, ISSN: 0146-9592, DOI: 10.1364/OL.33.001629
PAVEL KIŽEK: "Spatial light modulators in fluorescence microscopy", MICROSCOPY: SCIENCE , TECHNOLOGY, APPLICATIONS AND EDUCATION, vol. 2, 1 January 2010 (2010-01-01), pages 1366 - 1377, XP055323662
LIAO, Z.KASIRER-FRIEDE, A.SHATTIL, S. J.: "« Optogenetic interrogation of integrin αYβ3 function in endothelial cells » (Interrogation optogénétique de la fonction intégrine αYβ3 dans des cellules endothéliales", J. CELL SCI., vol. 130, 2017, pages 3532 - 3541
AXELROD, D.: "« Evanescent excitation and émission in fluorescence microscopy » (Excitation et émission évanescentes en microscopie à fluorescence", BIOPHYS. J., vol. 104, 2013, pages 1401 - 9
LAURENCE J. YOUNG ET AL: "A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors", JOURNAL OF VISUALIZED EXPERIMENTS, no. 111, 30 May 2016 (2016-05-30), XP055607172, DOI: 10.3791/53988
FIOLKA R ET AL: "Structured illumination in total internal reflection fluorescence microscopy using a spatial light modulator", OPTICS LETTERS, OPTICAL SOCIETY OF AMERICA, US, vol. 33, no. 14, 15 July 2008 (2008-07-15), pages 1629 - 1631, XP001514976, ISSN: 0146-9592, DOI: 10.1364/OL.33.001629
PAVEL KIŽEK: "Spatial light modulators in fluorescence microscopy", MICROSCOPY: SCIENCE , TECHNOLOGY, APPLICATIONS AND EDUCATION, vol. 2, 1 January 2010 (2010-01-01), pages 1366 - 1377, XP055323662
LIAO, Z.KASIRER-FRIEDE, A.SHATTIL, S. J.: "« Optogenetic interrogation of integrin αYβ3 function in endothelial cells » (Interrogation optogénétique de la fonction intégrine αYβ3 dans des cellules endothéliales", J. CELL SCI., vol. 130, 2017, pages 3532 - 3541
AXELROD, D.: "« Evanescent excitation and émission in fluorescence microscopy » (Excitation et émission évanescentes en microscopie à fluorescence", BIOPHYS. J., vol. 104, 2013, pages 1401 - 9
Attorney, Agent or Firm:
CABINET CHAILLOT (FR)
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