Title:
DEVICE FOR EXAMINING PLATELETS USING CLOGGING
Document Type and Number:
WIPO Patent Application WO/2017/191890
Kind Code:
A1
Abstract:
The present invention relates to a device for examining platelets using targeted clogging, comprising: a sample chamber storing a blood sample therein; a microfluidic channel which is in communication with the sample chamber, and through which the blood sample flows; and a microbead packing part installed in the flow path of the blood sample in the microfluidic channel, the microbead packing part comprising a packing conduit forming a part of the flow path of the sample solution, and a plurality of microbeads accommodated in the packing conduit such that the microbeads are in close contact with each other, thereby forming voids therebetween, such that platelet function examination is possible by means of the clogging of the voids due to platelets in the blood sample flowing from the sample chamber through the microfluidic channel. Accordingly, in the platelet function examination using clogging, substantial clogging can occur even with a small amount of a blood sample. Further, the reliability of the platelet examination can be increased by allowing a space between channels through which platelets flow, particularly a gap in a region clogged due to the occurrence of platelet adhesion and aggregation, to be maintained the same across devices.
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Inventors:
SHIN SE-HYUN (KR)
Application Number:
PCT/KR2017/001693
Publication Date:
November 09, 2017
Filing Date:
February 16, 2017
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
G01N33/49; B01L3/00
Foreign References:
KR20150124895A | 2015-11-06 | |||
KR101193566B1 | 2012-10-22 | |||
KR20140094036A | 2014-07-30 | |||
KR20110056497A | 2011-05-30 |
Other References:
SONG, SUK-HEUNG: "Migration distance-based platelet function analysis in a microfluidic system", BIOMICROFLUIDICS, vol. 7, no. 6, 2013, pages 1 - 10, XP055313679, DOI: doi:10.1063/1.4829095
Attorney, Agent or Firm:
NAMCHON INTERNATIONAL PATENT AND LAW FIRM (KR)
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