Title:
DEVICE FOR IMMOBILIZING CHEMICAL AND BIOMEDICAL SPECIES AND METHODS OF USING SAME
Document Type and Number:
WIPO Patent Application WO2005054441
Kind Code:
A3
Abstract:
A substrate is provided that facilitates immobilization of nucleic acid molecules, including DNA molecules and RNA molecules. Also provided is a device that includes the substrate, which, for example, can be a chip. In addition, methods of using the substrate are provided, including, for example, methods of sequencing a DNA molecule anchored to the substrate, and methods for conducting the process of sequencing using such devices.
Inventors:
QUAKE STEPHEN R (US)
KARTALOV EMIL (US)
KARTALOV EMIL (US)
Application Number:
PCT/US2004/040147
Publication Date:
November 09, 2006
Filing Date:
December 01, 2004
Export Citation:
Assignee:
CALIFORNIA INST OF TECHN (US)
QUAKE STEPHEN R (US)
KARTALOV EMIL (US)
QUAKE STEPHEN R (US)
KARTALOV EMIL (US)
International Classes:
C12Q1/68; B01J19/00; B01L3/00; F16K7/04; F16K31/145; C12N
Foreign References:
| US20020025529A1 | 2002-02-28 |
Other References:
GHOSH P. ET AL., ANGEW. CHEM. INT. ED. ENGL., vol. 38, no. 11, 1999, pages 1592 - 1595, XP003001879
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