Title:
DEVICE AND METHOD FOR FORMING CHONDROPROGENITOR CELL AGGREGATE
Document Type and Number:
WIPO Patent Application WO/2023/055072
Kind Code:
A1
Abstract:
A device for forming a chondroprogenitor cell aggregate according to the present embodiment comprises: a plurality of wells in each of which a micromass is disposed; an electrical stimulation unit which provides electrical stimulation to the micromasses; an image acquisition unit which acquires images by photographing, at predetermined time intervals, the micromasses disposed in the plurality of wells; and a stimulation provision determination unit which determines from the images whether to provide electrical stimulation, wherein the stimulation provision determination unit determines whether to provide the electrical stimulation from a degree of aggregation of the micromass provided with the electrical stimulation.
Inventors:
YOO SEUNG HO (KR)
CHANG CHI YOUNG (KR)
CHANG CHI YOUNG (KR)
Application Number:
PCT/KR2022/014557
Publication Date:
April 06, 2023
Filing Date:
September 28, 2022
Export Citation:
Assignee:
YOUTH BIO GLOBAL CO LTD (KR)
International Classes:
C12M1/42; A61L27/36; A61L27/38; C12M1/32; C12M3/00; C12N5/077; C12N13/00; G01N33/50
Foreign References:
| KR101603475B1 | 2016-03-15 | |||
| KR20190070096A | 2019-06-20 | |||
| KR101653197B1 | 2016-09-01 | |||
| KR20150108963A | 2015-10-01 |
Other References:
MATTA CSABA, ZAKANY ROZA: "Calcium signalling in chondrogenesis implications for cartilage repair", FRONTIERS IN BIOSCIENCE (SCHOLAR EDITION), FRONTIERS IN BIOSCIENCE, SEARINGTON, US, vol. S5, no. 1, 1 January 2013 (2013-01-01), Searington, US , pages 305 - 324, XP093052862, ISSN: 1945-0516, DOI: 10.2741/S374
KWON, HYUCK JOON: "Development of cell therapy for cartilage regeneration using electrical stimulation-based technology for chondrogenesis of human mesenchymal stem cells", GOVERNMENT PROJECT FINAL REPORT, 2019, pages 1 - 24
KWON, HYUCK JOON: "Development of cell therapy for cartilage regeneration using electrical stimulation-based technology for chondrogenesis of human mesenchymal stem cells", GOVERNMENT PROJECT FINAL REPORT, 2019, pages 1 - 24
Attorney, Agent or Firm:
ISIS IP LAW LLC (KR)
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