Title:
DEVICE AND METHODS FOR THE DETECTION OF CERVICAL DISEASE
Document Type and Number:
WIPO Patent Application WO/2012/088195
Kind Code:
A3
Abstract:
The present invention discloses a novel device and methods thereof with utility application in the high-throughput detection, screening and disease management of cervical disease. The "multiwell" device of the present invention consists of a solid support featuring multiple well-separated areas, each accommodating a patient sample, leading to simultaneous evaluation of patient samples. The methods of the present invention comprise conventional cytological staining, cervical Pap staining, and immunochemical staining using antibodies or combination of antibodies which are capable of binding to biomarkers that are overexpressed in cancer including in cervical carcinoma and dysplasia, as compared to normal controls. The device and methods of the present invention can be practiced in either manual or automated mode, and applied to any biological fluid or cell suspension from any biological specimen in view of a variety of cell biology assays, and in view of detection and screening of cervical and other diseases.
Inventors:
MONCEF JENDOUBI (US)
Application Number:
PCT/US2011/066317
Publication Date:
October 26, 2012
Filing Date:
December 20, 2011
Export Citation:
Assignee:
MILAGEN INC (US)
MONCEF JENDOUBI (US)
MONCEF JENDOUBI (US)
International Classes:
G01N33/574; G01N33/15; G01N33/543
Domestic Patent References:
| WO2010041349A1 | 2010-04-15 |
Foreign References:
| US20020009724A1 | 2002-01-24 | |||
| US20080199852A1 | 2008-08-21 | |||
| US20060154275A1 | 2006-07-13 |
Attorney, Agent or Firm:
MILAGEN, INC. (Suite BEmeryville, CA, US)
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