Title:
DEVICE, PLATFORM, AND ASSAY FOR ASSESSING CELLS
Document Type and Number:
WIPO Patent Application WO/2016/132221
Kind Code:
A3
Abstract:
This invention provides devices capable of assessing the migration response in the presence of a stable encapsulated gradient of a factor or factor combination, and quantifying the adherence response inside micro-channels in the presence of different factors. This invention also provides a piatform for obtaining information relating to migration score or the quantification of adhered cells through use of the devices of the present invention, and it allows this information to be used to assess therapeutic potential Additionally, the invention provides a method to quantify the cells migration response and the cell adherence response.
Inventors:
COX JUAN PABLO ACEVEDO (CL)
Application Number:
PCT/IB2016/000274
Publication Date:
October 13, 2016
Filing Date:
February 22, 2016
Export Citation:
Assignee:
CELLS FOR CELLS S A (CL)
International Classes:
B01L3/00; C12Q1/02; G01N33/48; G01N33/50; G01N33/53
Domestic Patent References:
| WO2014042463A1 | 2014-03-20 |
Foreign References:
| US20110117579A1 | 2011-05-19 | |||
| US5637469A | 1997-06-10 | |||
| US20060160066A1 | 2006-07-20 | |||
| US20090136982A1 | 2009-05-28 | |||
| US20150018226A1 | 2015-01-15 |
Other References:
ANNABI, N ET AL.: "Hydrogel-coated microfluidic channels for cardiomyocyte culture.", LAB ON A CHIP., vol. 13, 2013, pages 3569 - 3577, XP055321101
See also references of EP 3259066A4
See also references of EP 3259066A4
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